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12404 Cbln1

12404

Cbln1

cerebellin 1 precursor protein

protein-coding

Mus musculus

基因描述

Type Description
Definition cerebellin 1 precursor protein

研究结论

Date Results Publications
2021-03-13 13:24:00 GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells. 33352118
2019-07-13 12:13:00 Cbln4 partially rescued and both glycosylation mutants completely rescued ataxia in cbln1-null mice 29782851
2018-05-05 10:02:00 Results show that Cbln1, Cbln2, and Cbln4 are abundantly expressed in nearly all brain regions, but exhibit strikingly different expression patterns and developmental dynamics. Using newly generated knockin reporter mice for Cbln2 and Cbln4, we find that Cbln2 and Cbln4 are not universally expressed in all neurons, but only in specific subsets of neurons. 28714144
2017-08-05 11:38:00 results suggest that gene and seizure interactions in ventral tegmental area glutamatergic neurons impair sociability by downregulating Cbln1, a key node in the expanding protein interaction network of autism genes 28297715
2017-07-22 11:38:00 Despites its well known role in motor coordination and motor learning, whether and how the cerebellum is involved in cognitive functions remains less clear. Cerebellin 1 (Cbln1) is highly expressed in the cerebellum and serves as an essential synaptic organizer. Although genes encoding Cbln1 and its receptor are associated with many psychiatric disorders, it remains unknown whether such cognitive impairments are caused by 27852787

名称对应

Type IDs
Synonymous AI323299
Gene
UniProtKB-ID: CBLN1_MOUSE, Q7TNF5_MOUSE
UniprotKB: Q9R171, Q7TNF5
UniParc: UPI000002383D
EMBL: AF164680, BC132122, X61448, BC132120, BC055730
Ensembl: ENSMUSG00000031654
KO: mmu:12404
Nucleutide sequences
EMBL-CDS: CAA43688.1, AAD47280.1, AAI32121.1, AAH55730.2, AAI32123.1
Ensembl_TRS: ENSMUST00000169693, ENSMUST00000034076
Protein sequencees
Ensembl_PRO: ENSMUSP00000034076, ENSMUSP00000126575
RefSeq: NP_062600.2
Others
UniRef100: UniRef100_Q9R171
UniRef90: UniRef90_Q9R171
UniRef50: UniRef50_Q9R171
UniGene: Mm.4880
CCDS: CCDS22506.1

全选

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