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12398 Cbfa2t3

12398

Cbfa2t3

CBFA2/RUNX1 translocation partner 3

protein-coding

Mus musculus

基因描述

Type Description
Definition CBFA2/RUNX1 translocation partner 3

研究结论

Date Results Publications
2020-11-21 13:28:00 Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization. 32960220
2020-05-02 12:33:00 The pluripotency regulator PRDM14 requires the master hematopoietic regulator CBFA2T3 to initiate leukemia in progenitor cells, demonstrating an oncogenic role for CBFA2T3 and providing an avenue for targeting cancer-initiating cells. 31015254
2019-01-19 11:33:00 Study reveals a complex pattern of gene regulation by SCL, ETO2 and RYBP. Genome-wide analyses shows locus-specific binding of ETO2 and RYBP on SCL's 778 activated and repressed genes. 30560907
2016-02-27 10:52:00 gene deficient mice have decreased levels of systemic monocytes and infarct-associated macrophages and display compromised tissue healing and post-MI heart failure 25957903
2015-05-16 10:40:00 MTG16 loss promotes radioresistance and impacts intestinal stem cell function, possibly due to shifting cellular response away from DNA damage-induced apoptosis and towards DNA repair after injury. 25573176

名称对应

Type IDs
Synonymous A630044F12Rik, AI465270, AW229127, Cbfa2t3h, ETO-2, Eto2, MTGR2
Gene
UniProtKB-ID: MTG16_MOUSE, B7ZP57_MOUSE, E9QM80_MOUSE
UniprotKB: O54972, B7ZP57, E9QM80
UniParc: UPI0000357C2C, UPI00015D7760, UPI0000020F67, UPI00015D7761
EMBL: AC151999, BC151156, BC141396, AK033680, AF038029, BC055951
Ensembl: ENSMUSG00000006362
KO: mmu:12398
Nucleutide sequences
EMBL-CDS: AAB92651.1, AAH55951.1, BAC28426.1, AAI41397.1, AAI51157.1
Ensembl_TRS: ENSMUST00000006525, ENSMUST00000127984, ENSMUST00000064674
Protein sequencees
Ensembl_PRO: ENSMUSP00000006525, ENSMUSP00000118997, ENSMUSP00000065728
RefSeq: XP_011246595.1, NP_033954.2, XP_030099131.1, XP_030099129.1, XP_030099127.1, XP_011246594.1, XP_030099130.1, NP_796263.1, XP_017168036.1, XP_030099128.1, XP_011246593.1, NP_001103343.1, XP_011246591.2
Others
UniRef100: UniRef100_O54972, UniRef100_B7ZP57, UniRef100_E9QM80
UniRef90: UniRef90_O54972, UniRef90_E9QM80
UniRef50: UniRef50_D4A303, UniRef50_O54972
UniGene: Mm.194339
CCDS: CCDS52696.1, CCDS22744.1

全选

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研究热度

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