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12395 Runx1t1

12395

Runx1t1

RUNX1 translocation partner 1

protein-coding

Mus musculus

基因描述

Type Description
Definition RUNX1 translocation partner 1

研究结论

Date Results Publications
2018-06-30 11:22:00 Results suggest that AML1/ETO expression determines a more mobile and less adherent phenotype in preleukemic cells, therefore altering the interaction with the hematopoietic niche, potentially leading to the migration across the bone marrow barrier and to disease progression 27713544
2018-01-06 10:12:00 The data suggest that the tumor suppressor activity of both RUNX1t1 and TFF1 are mechanistically connected to CEBPB and that cross-regulation between CEBPB-RUNX1t1-TFF1 plays an important role in gastric carcinogenesis. 27522676
2017-09-23 10:36:00 RUNX1T1 serves as a common angiogenic driver for vaculogenesis and functionality of endothelial lineage cells 28640846
2017-09-16 11:53:00 Leukaemogenesis by AML1-ETO requires enhanced C/D box snoRNA/RNP formation. 28650479
2012-04-07 12:12:00 Data show that RUNX1-ETO;c-Kit(T417IDelta418-419) coexpression promoted exclusively acute myeloid leukemia (AML) in a fraction (51%) of reconstituted mice. 21937700

名称对应

Type IDs
Synonymous Cbfa2t1h, ETO, MTG8
Gene
UniProtKB-ID: MTG8_MOUSE, B1AXH8_MOUSE, Q8C066_MOUSE, B1AXH9_MOUSE, Q3UQX8_MOUSE
UniprotKB: Q61909, B1AXH8, Q8C066, B1AXH9, Q3UQX8
UniParc: UPI00000EA33B, UPI00001F1A65, UPI00005665AB, UPI0000029261
EMBL: AK032132, BC139200, BC139201, AL844572, AL807804, AL824702, AK142006, D32007
Ensembl: ENSMUSG00000006586
KO: mmu:12395
Nucleutide sequences
EMBL-CDS: BAA06774.1, BAC27719.1, AAI39201.1, AAI39202.1, BAE24910.1
Ensembl_TRS: ENSMUST00000098256, ENSMUST00000105566, ENSMUST00000098257, ENSMUST00000006761
Protein sequencees
Ensembl_PRO: ENSMUSP00000095856, ENSMUSP00000095857, ENSMUSP00000127109, ENSMUSP00000006761
RefSeq: NP_001104496.1, XP_030108978.1, XP_006537635.1, NP_001104497.1, XP_030108979.1, XP_030108980.1, XP_006537632.1, XP_006537634.1, XP_006537631.1, NP_033952.1, XP_030108981.1, XP_030108976.1
Others
UniRef100: UniRef100_Q8C066, UniRef100_B1AXH8, UniRef100_Q61909, UniRef100_Q3UQX8
UniRef90: UniRef90_Q61909
UniRef50: UniRef50_Q61909
UniGene: Mm.4909, Mm.470961
CCDS: CCDS17978.1

全选

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研究热度

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