Type | Description |
---|---|
Definition | catenin (cadherin associated protein), alpha 1 |
Date | Results | Publications |
---|---|---|
2020-01-11 10:41:00 | beta-catenin has an TCF/LEF-independent nuclear function that coordinates an extensive network of myogenic genes in cooperation with MyoD; and an alpha-catenin-dependent membrane function that helps control cell-cell interactions | 30683662 |
2019-10-26 10:21:00 | alpha-catenin represents a bona fide tumor suppressor for the development of lobular-type breast cancer and as such provides an alternative event to E-cadherin inactivation, adherens junction dysfunction, and subsequent constitutive actomyosin contraction. | 29774524 |
2019-09-07 12:33:00 | alphaE-catenin knockout caused heart failure, the upregulation of hypertrophic genes, and the dysregulation of fatty acid metabolism via the transcriptional activity of Yap and beta-catenin. | 29923116 |
2018-09-15 10:25:00 | alphaE-catenin is essential for inhibiting nuclear YAP localization and cell proliferation. This function of alphaE-catenin is required for formation of the tooth signalling centre, the enamel knot (EK), which maintains dental mesenchymal condensation and epithelial invagination. alphaE-catenin restricts YAP/TAZ activity to establish a group of non-dividing and specialized cells that constitute a signalling centre. | 27405641 |
2018-04-28 10:24:00 | Catna1 functions as a positive regulator of pancreatic islet cell lineage differentiation by repressing the sonic hedgehog pathway. | 28793255 |
Type | IDs |
---|---|
Synonymous | 2010010M04Rik, AA517462, AI988031, Catna1 |
Gene |
UniProtKB-ID:
CTNA1_MOUSE,
Q545R0_MOUSE
UniprotKB:
P26231,
Q545R0
UniParc:
UPI0000003E89
EMBL:
AK159339,
X59990,
AK004623,
AK148496,
D90362,
BC048163,
BC105576
Ensembl:
ENSMUSG00000037815
KO:
mmu:12385
|
Nucleutide sequences |
EMBL-CDS:
AAH48163.1,
BAA14376.1,
CAA42607.1,
BAB23418.1,
AAI05577.1,
BAE28588.1,
BAE35001.1
Ensembl_TRS:
ENSMUST00000042345
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000049007
RefSeq:
XP_036016847.1,
NP_033948.1,
XP_006525611.1,
XP_030106159.1
|
Others |
UniRef100:
UniRef100_P26231
UniRef90:
UniRef90_P26231
UniRef50:
UniRef50_P26231
UniGene:
Mm.18962
CCDS:
CCDS29139.1
|
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Refseq |
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