| Type | Description |
|---|---|
| Definition | C-C motif chemokine receptor 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Chemokine (C-C Motif) Ligand 1 Derived from Tumor-Associated Macrophages Contributes to Esophageal Squamous Cell Carcinoma Progression via CCR8-Mediated Akt/Proline-Rich Akt Substrate of 40 kDa/Mammalian Target of Rapamycin Pathway. | 33460563 |
| 2020-10-10 12:59:00 | ARNT-dependent CCR8 reprogrammed LDH isoform expression correlates with poor clinical outcomes of prostate cancer. | 32319143 |
| 2019-05-25 10:57:00 | Blocking CCR8 via a small molecule inhibitor or short hairpin (sh)RNA mitigated the decrease in Ecadherin, and increase in MMP2 and VEGFC, caused by human recombinant (r)CCL18. CCR8 knockdown by shRNA reversed rCCL18induced cancer cell invasion, migration and epithelialmesenchymal transition | 30592282 |
| 2019-02-16 10:12:00 | Long-lived memory T cells in human skin can be defined by the expression of CCR8. | 29427415 |
| 2018-05-26 10:09:00 | Authors demonstrate the pivotal role of CCR8(+) Treg cells in restraining immunity and highlight the potential clinical implications of this discovery. | 28533380 |
| Type | IDs |
|---|---|
| Synonymous | CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1 |
| Gene |
UniProtKB-ID:
CCR8_HUMAN
UniprotKB:
P51685
UniParc:
UPI00005C40D8,
UPI0000043587
EMBL:
AF005210,
BC107152,
BC074743,
AC104850,
AK314957,
D49919,
BC069067,
AY016370,
BC107159,
U45983,
Z79782,
Y08456,
U62556,
CH471055
Ensembl:
ENSG00000179934
KO:
hsa:1237
|
| Nucleutide sequences |
EMBL-CDS:
AAB61962.1,
AAB05542.1,
AAI07153.1,
AAB62547.1,
CAA69712.1,
BAA23387.1,
AAH69067.1,
CAB02142.1,
EAW64577.1,
BAG37461.1,
AAK08628.1,
AAH74743.1,
AAI07160.1
Ensembl_TRS:
ENST00000326306
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000326432
RefSeq:
NP_005192.1
|
| Others |
UniRef100:
UniRef100_P51685
UniRef90:
UniRef90_P51685
UniRef50:
UniRef50_P51685
UniGene:
Hs.113222
CCDS:
CCDS2684.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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