| Type | Description |
|---|---|
| Definition | caspase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense. | 32298652 |
| 2020-11-21 13:26:00 | Caspase-6 Knockout in the 5xFAD Model of Alzheimer's Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks. | 32050445 |
| 2020-07-25 10:22:00 | Study demonstrates caspase-6 promotes hypoxia-induced neuronal damage through neurite retraction. The hypoxic stress activated caspase-6 within the neurite, leading to microtubule disassembly and neurite retraction. | 30417658 |
| 2019-09-21 12:27:00 | Caspase-6 impaired synaptic transmission and induced neurodegeneration in hippocampal CA1 neurons, but not in striatal medium spiny neurons. These data revealed that active Caspase-6 in the striatal medium spiny neurons failed to induce inflammation, neurodegeneration or behavioral abnormalities | 29352267 |
| 2019-07-20 10:23:00 | Casp6 may help regulate progenitors of B cells and early B-lineage cells. Casp6 regulates B-cell programs both during early development and after antigen stimulation in the periphery. | 29863787 |
| Type | IDs |
|---|---|
| Synonymous | CASP-6, Mch2 |
| Gene |
UniProtKB-ID:
CASP6_MOUSE,
Q3TPJ9_MOUSE
UniprotKB:
O08738,
Q3TPJ9
UniParc:
UPI0000022D73
EMBL:
AK165998,
AK146363,
Y13087,
AK164321,
AK168842
Ensembl:
ENSMUSG00000027997
KO:
mmu:12368
|
| Nucleutide sequences |
EMBL-CDS:
CAA73529.1,
BAE37737.1,
BAE40665.1,
BAE27113.1,
BAE38509.1
Ensembl_TRS:
ENSMUST00000029626
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029626
RefSeq:
NP_033941.3
|
| Others |
UniRef100:
UniRef100_O08738
UniRef90:
UniRef90_O35397
UniRef50:
UniRef50_P55212
UniGene:
Mm.281379
CCDS:
CCDS17838.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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