| Type | Description |
|---|---|
| Definition | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:11:00 | Haploinsufficiency of X-linked intellectual disability gene CASK induces post-transcriptional changes in synaptic and cellular metabolic pathways. | 32305418 |
| 2020-02-29 11:33:00 | CASK can induce the recurrence of Focal and Segmental GlomeruloSclerosis after renal transplantation. | 31356645 |
| 2020-02-15 11:55:00 | Authors ascertain that a large fraction of endogenous CNTNAP2, CASK, and GluA1 molecules collectively colocalize together in a tripartite manner. Individual knockdown of either CNTNAP2 or CASK similarly alter GluA1 levels and localization. These findings offer insight to molecular mechanisms underlying GluA1 regulation in interneurons. | 30779956 |
| 2019-12-28 12:15:00 | Our results demonstrate that mosaic or global reduction in CASK expression and/or function disproportionately affects retinal ganglion cells (RGCs). CASK expression in RGCs does not appear critical for cell survival, indicating a noncell autonomous role for CASK in the development of optic nerve. | 31425583 |
| 2018-01-13 12:18:00 | CASK T740A mutation attenuated the interaction between CASK and TBR1 in the brain. However, CASK T740A mice were generally healthy, without obvious defects in brain morphology. The most dramatic defect among the mutant mice was in extinction of associative memory, though acquisition was normal. | 28234597 |
| Type | IDs |
|---|---|
| Synonymous | DXPri1, DXRib1, LIN-2, Pals3, mLin-2 |
| Gene |
UniProtKB-ID:
CSKP_MOUSE,
B9EJ23_MOUSE
UniprotKB:
O70589,
B9EJ23
UniParc:
UPI00001F8080,
UPI000021922C,
UPI0000E6A7A8,
UPI0000F6E6DB,
UPI0000F6E6DC,
UPI000192C443
EMBL:
BC141292,
Y17138,
BX005215,
AL672204,
AL671117,
AK136523,
Y17137
Ensembl:
ENSMUSG00000031012
KO:
mmu:12361
|
| Nucleutide sequences |
EMBL-CDS:
BAE23024.1,
CAA76646.1,
CAA76647.1,
AAI41293.1
Ensembl_TRS:
ENSMUST00000115438,
ENSMUST00000115436,
ENSMUST00000033321
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000111096,
ENSMUSP00000033321,
ENSMUSP00000111098
RefSeq:
XP_006527623.1,
XP_036017693.1,
NP_001271434.1,
XP_017173858.1,
XP_011245738.1,
XP_036017695.1,
XP_017173857.1,
XP_017173856.1,
XP_036017690.1,
XP_036017694.1,
XP_011245741.1,
XP_017173860.1,
XP_036017691.1,
XP_011245733.1,
XP_006527624.1,
XP_011245735.1,
NP_001271432.1,
XP_036017689.1,
XP_017173859.1,
XP_011245743.1,
NP_001271433.1,
XP_017173855.1,
XP_011245742.1,
XP_011245739.1,
NP_033936.2,
XP_036017692.1,
XP_011245740.1,
XP_011245734.1,
XP_011245736.1,
XP_011245737.1
|
| Others |
UniRef100:
UniRef100_O70589,
UniRef100_B9EJ23
UniRef90:
UniRef90_O14936,
UniRef90_A0A2U3TZN6
UniRef50:
UniRef50_O14936,
UniRef50_Q62915
UniGene:
Mm.327591,
Mm.474948
CCDS:
CCDS40878.1,
CCDS72343.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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