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12353 Car6

12353

Car6

carbonic anhydrase 6

protein-coding

Mus musculus

基因描述

Type Description
Definition carbonic anhydrase 6

研究结论

Date Results Publications
2018-05-26 11:44:00 the nuclear localized CA-VI B selectively promotes IL-12 expression by interaction with protein arginine N-methyltransferase 5 (PRMT5), which reduces symmetric dimethylation of histone H3 arginine 8 modification (H3R8me2s) at Il12 promoters to facilitate chromatin accessibility, selectively enhancing c-Rel binding to the Il12b promoter. 28739930
2018-01-06 11:08:00 he altered biological processes included antigen transport by M-cells, potassium transport, muscle contraction, and thyroid hormone synthesis. Immunohistochemical staining confirmed the absence of CA VI in the submandibular gland of Car6 (-/-) mice 27209317
2015-04-04 12:32:00 knockout mouse model confirms that CA VI is involved in bitter taste perception. CA VI may be one of the factors which contribute to avoidance of bitter, potentially harmful, substances. 25134447
2011-10-01 10:24:00 The generation of Car6 (-/-) mice and examination of the effects of CAVI deficiency on gene transcription have revealed several affected clusters of biological processes, which implicate CAVI in catabolic processes and the immune system response. 20835760
2011-02-26 11:32:00 Car4, Car6, and Car12 showed moderate expression levels in the mouse harderian gland. 20820888

名称对应

Type IDs
Synonymous Ca6, DOC1
Gene
UniProtKB-ID: CAH6_MOUSE, Q3V197_MOUSE, Q3TTT1_MOUSE
UniprotKB: P18761, Q3V197, Q3TTT1
UniParc: UPI000002306A, UPI00005AB8A8, UPI00005B1D04
EMBL: AK161216, AL606903, AF079835, AK132599, CH466594
Ensembl: ENSMUSG00000028972
KO: mmu:12353
Nucleutide sequences
EMBL-CDS: AAD12540.1, EDL14887.1, BAE21254.1, BAE36243.1
Ensembl_TRS: ENSMUST00000030817
Protein sequencees
Ensembl_PRO: ENSMUSP00000030817
RefSeq: NP_033932.2
Others
UniRef100: UniRef100_Q3V197, UniRef100_P18761
UniRef90: UniRef90_P18761
UniRef50: UniRef50_P18761
UniGene: Mm.232523
CCDS: CCDS51386.1

全选

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