| Type | Description |
|---|---|
| Definition | carbonic anhydrase 5a, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2018-11-24 10:18:00 | In this report, genetic knockdown and overexpression studies confirm that mitochondrial CA VA regulates respiration in pericytes, whereas mitochondrial CA VB does not contribute significantly. Identification of mitochondrial CA VA as a sole regulator of respiration provides a specific target to develop new drugs with fewer side effects that may be better tolerated and can protect the brain from diabetic injury. | 28131914 |
| 2013-06-29 11:28:00 | both Car5A and Car5B contribute to both ammonia detoxification (ureagenesis) and regulation of fasting blood sugar (gluconeogenesis). | 23589845 |
| 2010-01-21 00:00:00 | determination of crystal structure | 11851394 |
| Type | IDs |
|---|---|
| Synonymous | CAV, Ca5a, Car5 |
| Gene |
UniProtKB-ID:
CAH5A_MOUSE
UniprotKB:
P23589
UniParc:
UPI0000001A7D
EMBL:
BC030174,
X51971
Ensembl:
ENSMUSG00000025317
KO:
mmu:12352
|
| Nucleutide sequences |
EMBL-CDS:
AAH30174.1,
CAA36233.1
Ensembl_TRS:
ENSMUST00000057653
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000060457
RefSeq:
NP_031634.2
|
| Others |
UniRef100:
UniRef100_P23589
UniRef90:
UniRef90_P23589
UniRef50:
UniRef50_P23589
UniGene:
Mm.116761
CCDS:
CCDS22731.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29768498 |
Genomic variants in an inbred mouse model predict mania-like behaviors. PLoS One Michael C Saul , Sharon A Stevenson , Changjiu Zhao , Terri M Driessen , Brian E Eisinger , Stephen C Gammie |
2018-01-01 | - |
| 28131914 |
Biochim Biophys Acta Mol Basis Dis Tulin O Price , Nader Sheibani , Gul N Shah |
2017-04-01 | - |
| 23589845 |
Proc. Natl. Acad. Sci. U.S.A. Gul N Shah , Timothy S Rubbelke , Joshua Hendin , Hien Nguyen , Abdul Waheed , James D Shoemaker , William S Sly |
2013-04-30 |
Car5a,
Car5b
|
| 23233153 |
A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development. Dev. Dyn. Ling Wu , Borum Sagong , Jae Young Choi , Un-Kyung Kim , Jinwoong Bok |
2013-03-01 |
Bglap,
Bglap2,
Bmp15,
Car8,
Car1,
Car11,
Car2,
Car3,
Car4,
Car5a,
Car6,
Car7,
Pou3f4,
Car9,
Car14,
Car5b,
Smpx,
Car13,
Car10,
Car12,
Car15
|
| 22109883 |
Endocrinology Tulin O Price , Vijay Eranki , William A Banks , Nuran Ercal , Gul N Shah |
2012-01-01 |
Car5a,
Car5b
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 17626619 |
An analysis of expression patterns of genes encoding proteins with catalytic activities. BMC Genomics Murat Cankaya , Ana Martinez Hernandez , Mehmet Ciftci , Sukru Beydemir , Hasan Ozdemir , Harun Budak , Ilhami Gulcin , Veysel Comakli , Tufan Emircupani , Deniz Ekinci , Muslum Kuzu , Qiuhong Jiang , Gregor Eichele , Omer Irfan Kufrevioglu |
2007-01-01 |
Rnaset2a,
Gck,
Aco1,
Aco2,
Adh1,
Aldoa,
Aldoc,
Car8,
Car1,
Car11,
Car2,
Car3,
Car4,
Car5a,
Car6,
Car7,
Cs,
Dld,
Eno1,
Eno2,
Eno3,
Fh1,
Gapdh,
Gapdhs,
Gpi1,
Hk1,
Hk2,
Idh1,
Idh3g,
Loxl3,
Idh3b,
Mdh2,
Mdh1,
Ogdh,
Pfkl,
Pfkm,
Pgam1,
Pgk1,
Pkm,
Pklr,
Ptgds,
Sucla2,
Suclg2,
Hk3,
Tpi1,
Aldob,
Car14,
Pla2g2f,
Idh2,
Pgam2,
Car5b,
Pfkp,
Suclg1,
Sdhc,
Sdhd,
Sdha,
Sdhb,
Idh3a,
Rnaset2b,
Acss1,
Csl,
Car13,
Car10,
Car12,
Dlst,
Car15,
Cpn1
|
| 17362527 |
A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system. BMC Mol. Biol. Pei-wen Pan , Alejandra Rodriguez , Seppo Parkkila |
2007-01-01 |
Car1,
Car2,
Car3,
Car4,
Car5a,
Car6,
Car7,
Car9,
Car14,
Car5b,
Car13,
Car12,
Car15
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员