| Type | Description |
|---|---|
| Definition | calpain 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 10:37:00 | Study shows that impaired skeletal muscle regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis. | 29241457 |
| 2017-09-30 13:50:00 | Destabilization of PGC1a is attributable to decreased p38 MAPK activation via diminished CaMKII signaling. Thus, we elucidate a pathway downstream of Ca(2+)-mediated CaMKII activation that is dysfunctional in C3KO(Capn3 knock-out mice ) mice, leading to reduced transcription of genes involved in muscle adaptation | 27005420 |
| 2016-10-22 12:05:00 | CAPN3 deficiency leads to degradation of SERCA proteins and Ca2+ dysregulation in the skeletal muscle. | 27055500 |
| 2016-10-01 12:20:00 | calpain 3 is necessary for ubiquitination and that it acts upstream of the ubiquitination machinery | 15961411 |
| 2016-04-30 11:19:00 | Cleavage of C-terminal titin by CAPN3 is associated with limb-girdle muscular dystrophy 2A and tibial muscular dystrophy. | 25877298 |
| Type | IDs |
|---|---|
| Synonymous | AI323605, Capa-3, Capa3, Lp82, p94 |
| Gene |
UniProtKB-ID:
CAN3_MOUSE,
A4QPE6_MOUSE,
Q0VGP9_MOUSE
UniprotKB:
Q64691,
A4QPE6,
Q0VGP9
UniParc:
UPI0000F7064F,
UPI0000566A53,
UPI0000566A55,
UPI0000566A54
EMBL:
AL935121,
X92523,
BC139790,
BC090661,
AF127766
Ensembl:
ENSMUSG00000079110
KO:
mmu:12335
|
| Nucleutide sequences |
EMBL-CDS:
AAD28255.2,
CAA63301.1,
AAI39791.1,
AAH90661.1
Ensembl_TRS:
ENSMUST00000110721,
ENSMUST00000028749,
ENSMUST00000028748
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106349,
ENSMUSP00000028749,
ENSMUSP00000028748
RefSeq:
NP_031627.2,
NP_001171270.1,
NP_001103231.1
|
| Others |
UniRef100:
UniRef100_Q0VGP9,
UniRef100_A4QPE6,
UniRef100_Q64691
UniRef90:
UniRef90_A4QPE6,
UniRef90_Q64691,
UniRef90_Q0VGP9
UniRef50:
UniRef50_P20807-2,
UniRef50_Q64691
UniGene:
Mm.458021,
Mm.485295
CCDS:
CCDS50679.1,
CCDS16620.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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