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12334 Capn2

12334

Capn2

calpain 2

protein-coding

Mus musculus

基因描述

Type Description
Definition calpain 2

研究结论

Date Results Publications
2020-12-12 13:24:00 Inhibition of the ERK1/2-ubiquitous calpains pathway attenuates experimental pulmonary fibrosis in vivo and in vitro. 32017927
2020-05-16 11:27:00 Heat stress reduces calpain-2 expression, which then activates p38, leading to cardiomyocyte apoptosis and heart dysfunction. 30417356
2019-10-26 11:14:00 Isoform-specific hyperactivation of calpain-2, but not calpain-1 occurs at the synapse early in the pathogenesis of Alzheimer's disease potentially contributing to the deregulation of synaptic signaling in humans and mice models. 30177812
2019-07-13 10:31:00 Our data indicate that calpain-1 activity is neuroprotective and calpain-2 activity is neurodegenerative after traumatic Brain Injury 28594313
2019-06-29 11:07:00 Following TBI, calpain-2 activation cleaved PTPN13, activated c-Abl and triggered tau tyrosine phosphorylation. 28924170

名称对应

Type IDs
Synonymous AI326419, CALP80, Capa-2, Capa2, m-calpain, m-calpin
Gene
UniProtKB-ID: CAN2_MOUSE
UniprotKB: O08529
UniParc: UPI000002793D
EMBL: D38117, BC054726, Y10139, AF015038
Ensembl: ENSMUSG00000026509
KO: mmu:12334
Nucleutide sequences
EMBL-CDS: AAB94029.1, BAA22964.1, CAA71227.1, AAH54726.1
Ensembl_TRS: ENSMUST00000068505
Protein sequencees
Ensembl_PRO: ENSMUSP00000068895
RefSeq: NP_033924.2
Others
UniRef100: UniRef100_O08529
UniRef90: UniRef90_Q07009
UniRef50: UniRef50_Q07009
UniGene: Mm.19306
CCDS: CCDS35813.1

全选

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研究热度

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