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12330 Canx

12330

Canx

calnexin

protein-coding

Mus musculus

基因描述

Type Description
Definition calnexin

研究结论

Date Results Publications
2021-02-20 13:36:00 EBV-induced gene 3 augments IL-23Ralpha protein expression through a chaperone calnexin. 32809973
2019-12-07 11:37:00 Study discovered that calnexin is highly abundant in human brain endothelial cells of multiple sclerosis (MS) patients. Conversely, mice lacking calnexin exhibited resistance to experimental autoimmune encephalomyelitis induction, no evidence of immune cell infiltration into the CNS. These findings identify a link between calnexin expression in CNS endothelial cells and neuroinflammation. 29515033
2014-01-25 10:47:00 CNX has a specific role in cardiomyocyte viability and Ca(2+) cycling through its effects on endoplasmic reticulum stress, apoptosis and Ca(2+) channel expression. 24037923
2013-11-30 10:05:00 Calnexin discriminates between different conformational states of GlyT2 displaying a lectin-independent chaperone activity. 23650557
2011-12-31 11:26:00 calnexin and ERp57, but not calreticulin, play an important role in the biology of peripheral myelin proteins PMP22 and P0, and, consequently, these chaperones may contribute to the pathogenesis of peripheral neuropathies 21831887

名称对应

Type IDs
Synonymous 1110069N15Rik, AI988026, Cnx, D11Ertd153e
Gene
UniProtKB-ID: CALX_MOUSE, Q5SUC3_MOUSE
UniprotKB: P35564, Q5SUC3
UniParc: UPI0000001916
EMBL: BC040244, AK084175, L23865, AK165508, AK166649, BC012408, L18888
Ensembl: ENSMUSG00000020368
KO: mmu:12330
Nucleutide sequences
EMBL-CDS: BAC39133.1, AAA21014.1, AAH12408.1, AAA62450.1, AAH40244.1, BAE38226.1, BAE38916.1
Ensembl_TRS: ENSMUST00000179865, ENSMUST00000020637
Protein sequencees
Ensembl_PRO: ENSMUSP00000137440, ENSMUSP00000020637
RefSeq: NP_031623.1, NP_001103969.1, NP_001103970.1
Others
UniRef100: UniRef100_P35564
UniRef90: UniRef90_P35565
UniRef50: UniRef50_P27824
UniGene: Mm.248827
CCDS: CCDS24633.1

全选

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