| Type | Description |
|---|---|
| Definition | abnormal spindle microtubule assembly |
| Date | Results | Publications |
|---|---|---|
| 2017-07-29 12:54:00 | in this study we have provided evidence that ASPM controls spindle orientation by regulating the dynamics of astral MT and that CITK is a critical downstream partner of ASPM for this activity. | 27562601 |
| 2017-07-29 10:20:00 | Aspm and Wdr62 interact genetically to control brain size, with mice lacking Wdr62, Aspm, or both showing gene dose-related centriole duplication defects that parallel the severity of the microcephaly and increased ectopic basal progenitors, suggesting premature delamination from the ventricular zone. | 27974163 |
| 2016-07-02 10:18:00 | Interaction between ASPM and the Cdk2/Cyclin E complex regulated the Cyclin activity by modulating its ubiquitination and localization into the nucleus. | 26581405 |
| 2016-03-05 11:04:00 | Aspm, a gene that is mutated in familial microcephaly, regulates postnatal neurogenesis in the cerebellum and supports the growth of medulloblastoma, the most common malignant pediatric brain tumor. | 26450969 |
| 2015-03-07 12:33:00 | Aspm is essential to the proliferation and differentiation of neural stem/progenitor cells. The Aspm gene loss model provided a novel pathogenetic insight into acquired microcephaly, which can be caused by in utero exposure teratogens. | 24220505 |
| Type | IDs |
|---|---|
| Synonymous | Calmbp1, D330028K02Rik, MCPH5, Sha1 |
| Gene |
UniProtKB-ID:
ASPM_MOUSE
UniprotKB:
Q8CJ27
UniParc:
UPI0000EE04B1,
UPI00006976B5
EMBL:
AF533752,
AF062378,
AY971958,
AC158946,
AK083710,
AL606536,
AK050785
Ensembl:
ENSMUSG00000033952
KO:
mmu:12316
|
| Nucleutide sequences |
EMBL-CDS:
BAC34410.2,
AAN46088.1,
AAY46816.1,
AAC79683.1,
BAC39000.1
Ensembl_TRS:
ENSMUST00000053364,
ENSMUST00000200083
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059159,
ENSMUSP00000142880
RefSeq:
XP_006529171.1,
NP_033921.3,
XP_017168446.1
|
| Others |
UniRef100:
UniRef100_Q8CJ27
UniRef90:
UniRef90_Q8CJ27
UniRef50:
UniRef50_Q8CJ27
UniGene:
Mm.168523
CCDS:
CCDS35729.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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