| Type | Description |
|---|---|
| Definition | calcium channel, voltage-dependent, beta 1 subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 11:07:00 | Data show that mutant variant V156A results in instability of protein subdomains of beta1a subunit leading to a phenotype of Ca(2+) dysregulation that partly resembles that of other malignant hypertension-linked mutations of DHPR alpha1S subunit. | 29212769 |
| 2017-06-10 11:54:00 | Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta1a reveal critical roles of domain interactions for stability. | 28351836 |
| 2016-12-17 10:44:00 | These results provide new insights into the role of muscle-specific proteins on the structural arrangement of alpha1S intracellular loops and point to a new conformational effect of the beta1a subunit in supporting skeletal muscle excitation-contraction coupling. | 27129199 |
| 2016-04-09 10:37:00 | The present study reveals that the C-terminal of the beta1a subunit changes conformation in the presence of RyR1 consistent with an interaction between the C-terminal of beta1a and RyR1 in resting myotubes. | 26114725 |
| 2015-10-31 10:25:00 | TnT3 facilitates Cavbeta1a nuclear recruitment, suggesting that the two proteins play a heretofore unknown role during early muscle differentiation in addition to their classical role in excitation-contraction coupling regulation. | 25981458 |
| Type | IDs |
|---|---|
| Synonymous | CAB1, Cchb1, Cchlb1 |
| Gene |
UniProtKB-ID:
CACB1_MOUSE,
A2A545_MOUSE,
A2A542_MOUSE,
A2A543_MOUSE
UniprotKB:
Q8R3Z5,
A2A545,
A2A542,
A2A543
UniParc:
UPI0000028480,
UPI00003B2584,
UPI00002145B6,
UPI00003B2585,
UPI0000027376,
UPI00001960CA,
UPI000002847E
EMBL:
AB100389,
AY094172,
AL591209,
AF322905,
AF068898,
AY094173
Ensembl:
ENSMUSG00000020882
KO:
mmu:12295
|
| Nucleutide sequences |
EMBL-CDS:
AAM11473.1,
AAG42829.1,
BAC80138.1,
AAC19386.1,
AAM11474.1
Ensembl_TRS:
ENSMUST00000107562,
ENSMUST00000092736,
ENSMUST00000107561,
ENSMUST00000017552
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103187,
ENSMUSP00000090412,
ENSMUSP00000103186,
ENSMUSP00000017552
RefSeq:
NP_660099.2,
NP_001269907.1,
XP_006532154.1,
NP_001152792.1,
NP_112450.1,
XP_006532155.1,
NP_001152791.1,
XP_030101359.1,
XP_030101360.1,
NP_001269906.1,
XP_036012148.1
|
| Others |
UniRef100:
UniRef100_A0A0R4J194,
UniRef100_A2A542,
UniRef100_Q8R3Z5,
UniRef100_A2A543
UniRef90:
UniRef90_Q8R3Z5-2,
UniRef90_Q8R3Z5,
UniRef90_A2A542
UniRef50:
UniRef50_Q9MZL7-2,
UniRef50_Q8R3Z5
UniGene:
Mm.41252
CCDS:
CCDS48899.1,
CCDS25335.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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