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12291 Cacna1g

12291

Cacna1g

calcium channel, voltage-dependent, T type, alpha 1G subunit

protein-coding

Mus musculus

基因描述

Type Description
Definition calcium channel, voltage-dependent, T type, alpha 1G subunit

研究结论

Date Results Publications
2021-03-13 13:21:00 Concomitant genetic ablation of L-type Cav1.3 (alpha1D) and T-type Cav3.1 (alpha1G) Ca(2+) channels disrupts heart automaticity. 33144668
2020-10-24 13:54:00 Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia. 30715245
2020-08-22 15:27:00 Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms. 31800012
2020-03-21 11:21:00 T-type channels Cav3.1and Cav3.2 do not contribute to baseline blood pressure levels and ANG II-induced hypertension. Cav3.1, but not Cav3.2, contributes to aldosterone secretion. Aldosterone promotes cardiac hypertrophy during hypertension. 31042060
2019-08-24 10:10:00 Loss of Cav3.1 makes the beating rates of the heart in vivo and perfused hearts ex vivo, as well as sinoatrial node cells, less sensitive to beta-adrenergic stimulation. 29274077

名称对应

Type IDs
Synonymous Cav3.1d, [a]1G, a1G, alpha-1G, mKIAA1123
Gene
UniProtKB-ID: Q9WUT2_MOUSE, Q5SUF6_MOUSE, Q5SUG1_MOUSE, Q6ZPX4_MOUSE, Q5SUG0_MOUSE, Q27YN9_MOUSE, Q5SUF9_MOUSE, Q5SUF7_MOUSE, Q6PFV8_MOUSE, Q5SUG3_MOUSE, Q5SUF5_MOUSE, Q5SUF8_MOUSE, Q5SUG4_MOUSE, E9PWL1_MOUSE
UniprotKB: Q9WUT2, Q5SUF6, Q5SUG1, Q6ZPX4, Q5SUG0, Q27YN9, Q5SUF9, Q5SUF7, Q6PFV8, Q5SUG3, Q5SUF5, Q5SUF8, Q5SUG4, E9PWL1
UniParc: UPI00001CDEC7, UPI0000470CFC, UPI000162B822, UPI00001E63D8, UPI00000E6BA0, UPI00006C96D1, UPI0000470CFB, UPI0000470CFD, UPI0000470CFE, UPI0000470CF8, UPI00001D4AC6, UPI0000470CFA, UPI0000192B8F, UPI0000470CF9
EMBL: AL645965, AJ012569, DQ317412, AK129294, BC057399
Ensembl: ENSMUSG00000020866
KO: mmu:12291
Nucleutide sequences
EMBL-CDS: CAB40793.1, BAC98104.1, ABC47034.1, AAH57399.1
Ensembl_TRS: ENSMUST00000103166, ENSMUST00000107786, ENSMUST00000107793, ENSMUST00000107790, ENSMUST00000107789, ENSMUST00000107788, ENSMUST00000107792, ENSMUST00000107791, ENSMUST00000100561, ENSMUST00000021234
Protein sequencees
Ensembl_PRO: ENSMUSP00000099455, ENSMUSP00000103415, ENSMUSP00000103422, ENSMUSP00000103419, ENSMUSP00000103418, ENSMUSP00000103417, ENSMUSP00000103421, ENSMUSP00000103420, ENSMUSP00000098127, ENSMUSP00000021234
RefSeq: XP_006532133.1, XP_006532138.1, XP_036012147.1, XP_006532136.1, XP_030101356.1, XP_006532132.1, NP_001171361.1, XP_011246999.1, XP_011246991.1, XP_006532151.1, XP_006532149.1, XP_006532144.1, XP_006532137.1, XP_011246997.1, XP_006532145.1, XP_011246990.1, XP_006532143.1, XP_006532142.1, XP_011246996.1, XP_006532135.1, XP_006532147.1, XP_006532139.1, XP_011246989.1, XP_011247000.1, XP_011246992.1, XP_006532150.1, NP_033913.2, XP_017169723.1, XP_011246988.1, XP_011246995.1, XP_011246998.1, XP_011247001.1, XP_011246994.1, XP_006532148.1, XP_030101357.1, XP_011246993.1, XP_017169724.1, NP_001106284.1, XP_006532146.1, NP_001171359.1, XP_011247002.1
Others
UniRef100: UniRef100_Q5SUF9, UniRef100_Q5SUF6, UniRef100_Q5SUF8, UniRef100_Q27YN9, UniRef100_Q6PFV8, UniRef100_Q5SUG4, UniRef100_Q5SUF7, UniRef100_Q5SUG3, UniRef100_Q9WUT2, UniRef100_Q5SUG0, UniRef100_Q5SUF5, UniRef100_Q5SUG1, UniRef100_Q6ZPX4, UniRef100_E9PWL1
UniRef90: UniRef90_Q6ZPX4, UniRef90_Q6PFV8, UniRef90_Q5SUF6, UniRef90_Q5SUG3, UniRef90_Q5SUG4, UniRef90_Q5SUG1, UniRef90_Q5SUF7, UniRef90_Q27YN9, UniRef90_E9PWL1, UniRef90_Q5SUF5, UniRef90_Q5SUF9, UniRef90_Q5SUG0, UniRef90_Q5SUF8
UniRef50: UniRef50_Q5SUF7, UniRef50_O43497-3, UniRef50_O43497-4
UniGene: Mm.29585

全选

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研究热度

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