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12288 Cacna1c

12288

Cacna1c

calcium channel, voltage-dependent, L type, alpha 1C subunit

protein-coding

Mus musculus

基因描述

Type Description
Definition calcium channel, voltage-dependent, L type, alpha 1C subunit

研究结论

Date Results Publications
2021-04-03 13:38:00 CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade. 32332705
2020-11-28 13:17:00 AKAP5 complex facilitates purinergic modulation of vascular L-type Ca(2+) channel CaV1.2. 33082339
2020-10-24 14:01:00 Blockade of microglial Cav1.2 Ca(2+) channel exacerbates the symptoms in a Parkinson's disease model. 31235768
2020-09-19 16:28:00 Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology. 32859919
2020-08-01 12:39:00 The results of the present study reveal a new facet of betaAR-mediated regulation of CaV 1.2 channels in the heart and support the novel concept that a pre-synthesized pool of sub-sarcolemmal CaV 1.2 channel-containing vesicles/endosomes resides in cardiomyocytes and can be mobilized to the sarcolemma to tune excitation-contraction coupling to meet metabolic and/or hemodynamic demands. 30714156

名称对应

Type IDs
Synonymous Cav1.2, Cchl1a1, D930026N18Rik, MBC, MELC-CC
Gene
UniProtKB-ID: CAC1C_MOUSE, C7TQ59_MOUSE, A0A087WS40_MOUSE, F8WJL1_MOUSE, F7C376_MOUSE, C7TQ61_MOUSE, C7TQ58_MOUSE, C7TQ60_MOUSE, Q0PCR6_MOUSE, C7TQ57_MOUSE, A0A087WSE7_MOUSE, C7TQ62_MOUSE
UniprotKB: Q01815, C7TQ59, A0A087WS40, F8WJL1, F7C376, C7TQ61, C7TQ58, C7TQ60, Q0PCR6, C7TQ57, A0A087WSE7, C7TQ62
UniParc: UPI0001B5FE82, UPI000241D717, UPI00019B254D, UPI0001B5FE7E, UPI0001B5FE7F, UPI0001B5FE81, UPI000241D712, UPI000241D716, UPI000002A59E, UPI0000029403, UPI000002A59F, UPI0001B5FE80, UPI0001B5FE7D, UPI0000DCFDBB
EMBL: FM872409, AB259049, AC163353, L06233, AC127328, AC126453, FM872414, AC115816, U17869, L01776, AC036121, FM872413, FM872412, FM872411, FM872410, M57973
Ensembl: ENSMUSG00000051331
KO: mmu:12288
Nucleutide sequences
EMBL-CDS: AAA63291.1, AAB59633.1, AAA37351.1, AAA62612.1, CAS06714.1, CAS06716.1, CAS06713.1, CAS06715.1, BAF03165.1, CAS06712.1, CAS06717.1
Ensembl_TRS: ENSMUST00000112825, ENSMUST00000078320, ENSMUST00000075591, ENSMUST00000187474, ENSMUST00000188106, ENSMUST00000112790, ENSMUST00000112793, ENSMUST00000186889, ENSMUST00000187940, ENSMUST00000190285
Protein sequencees
Ensembl_PRO: ENSMUSP00000077433, ENSMUSP00000075021, ENSMUSP00000108444, ENSMUSP00000140961, ENSMUSP00000140886, ENSMUSP00000108410, ENSMUSP00000108413, ENSMUSP00000140056, ENSMUSP00000141033, ENSMUSP00000141015
RefSeq: XP_030110985.1, XP_017176847.1, XP_006505495.1, XP_011239494.1, XP_006505502.1, XP_036021663.1, XP_011239487.1, NP_001242928.1, XP_011239495.1, XP_006505500.1, XP_036021670.1, XP_006505503.1, XP_036021672.1, XP_036021675.1, XP_006505481.1, XP_011239488.1, XP_006505497.1, XP_036021666.1, XP_036021673.1, NP_001242927.1, NP_033911.2, XP_006505504.1, XP_006505501.1, NP_001153007.1, XP_006505478.1, XP_011239477.1, XP_036021664.1, XP_036021669.1, XP_036021665.1, XP_036021671.1, XP_036021662.1, XP_036021674.1, XP_006505490.1, XP_006505499.1, XP_011239486.1, NP_001153005.1, XP_006505498.1, XP_036021668.1, XP_006505505.1, NP_001242926.1, NP_001277264.1, NP_001242930.1, NP_001153006.1, NP_001242929.1, XP_006505489.1, XP_006505506.1, XP_011239478.1, XP_011239489.1, XP_030110986.1, XP_006505493.1, NP_001242931.1, XP_036021667.1, XP_017176851.1
Others
UniRef100: UniRef100_Q01815, UniRef100_C7TQ59, UniRef100_C7TQ57, UniRef100_C7TQ61, UniRef100_F7C376, UniRef100_C7TQ62, UniRef100_F8WJL1, UniRef100_C7TQ58, UniRef100_A0A087WS40, UniRef100_A0A087WSE7, UniRef100_Q0PCR6, UniRef100_C7TQ60
UniRef90: UniRef90_F8WJL1, UniRef90_Q0PCR6, UniRef90_C7TQ61, UniRef90_Q13936-37, UniRef90_F7C376, UniRef90_A0A087WSE7, UniRef90_Q01815, UniRef90_C7TQ59, UniRef90_Q13936-4
UniRef50: UniRef50_Q13936-28, UniRef50_Q13936
UniGene: Mm.436656
CCDS: CCDS71821.1, CCDS80590.1

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