| Type | Description |
|---|---|
| Definition | hypoxia up-regulated 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 10:36:00 | The protein but not the mRNA level of ORP150, a nucleotide exchange factor which can substitute for SIL1, was increased in the cerebellum of GSK2606414-treated woozy mice, suggesting that translational recovery promoted the synthesis of this alternative BiP co-factor | 29718201 |
| 2017-04-15 11:32:00 | The relative increase in ORP150 mRNA observed in hypoxia, compared with normoxia, may support its cytoprotective role in oxygendeprived conditions | 27748851 |
| 2014-04-12 11:27:00 | Here we show that Grp170 can bind directly to a variety of incompletely folded protein substrates in the endoplasmic reticulum, and as expected for a bona fide chaperone, it does not interact with folded secretory proteins. | 24327659 |
| 2013-01-26 10:39:00 | These results suggest that although ORP150 is protective against bleomycin-induced lung injury, this protein could stimulate bleomycin-induced pulmonary fibrosis by increasing pulmonary levels of TGF-beta1 and myofibroblasts. | 22892132 |
| 2012-06-02 10:42:00 | Results reveal a previously unrecognized attribute of Grp170 as a superior DNA-binding chaperone capable of amplifying TLR9 activation on pathogen recognition. | 22207611 |
| Type | IDs |
|---|---|
| Synonymous | AI415631, CBP-140, Cab140, Grp170, Orp150 |
| Gene |
UniProtKB-ID:
HYOU1_MOUSE
UniprotKB:
Q9JKR6
UniParc:
UPI00000239B0
EMBL:
AK145857,
AF228709,
S78797,
BC050107,
AK157949,
AK171769,
AK155721
Ensembl:
ENSMUSG00000032115
KO:
mmu:12282
|
| Nucleutide sequences |
EMBL-CDS:
AAB35051.1,
BAE33401.1,
AAF65544.1,
AAH50107.1,
BAE34279.1,
BAE26702.1,
BAE42657.1
Ensembl_TRS:
ENSMUST00000160902,
ENSMUST00000161318,
ENSMUST00000066601
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000123700,
ENSMUSP00000068594,
ENSMUSP00000125594
RefSeq:
XP_006510023.1,
XP_006510022.1,
XP_006510025.1,
NP_067370.3,
XP_006510024.1
|
| Others |
UniRef100:
UniRef100_Q9JKR6
UniRef90:
UniRef90_Q9Y4L1
UniRef50:
UniRef50_Q9Y4L1
UniGene:
Mm.116721
CCDS:
CCDS23107.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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