| Type | Description |
|---|---|
| Definition | complement component 5a receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:33:00 | C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from gammadelta-T cells. | 32557852 |
| 2020-12-26 13:11:00 | Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis. | 32332099 |
| 2020-09-26 13:03:00 | The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury. | 31029505 |
| 2020-06-06 11:00:00 | Growth of B16.F0 melanoma tumors was reduced in C5aR1-/- mice. C5aR1 signaling supports melanoma growth by promoting infiltration of immunosuppressive leukocyte populations into the tumor microenvironment. | 31298935 |
| 2020-05-09 12:20:00 | identify C5aR1 activation as an important driver of IgE-mediated food allergy through regulation of allergen-specific IgE production, FcepsilonR1-mediated MC degranulation, and histamine-driven effector functions preferentially in male mice. | 30341777 |
| Type | IDs |
|---|---|
| Synonymous | C5aR, C5r1, Cd88, D7Msu1 |
| Gene |
UniProtKB-ID:
C5AR1_MOUSE
UniprotKB:
P30993
UniParc:
UPI00004CEC62
EMBL:
AY220494,
BC125641,
AC156630,
AK158027,
S50577,
BC125643,
S46665
Ensembl:
ENSMUSG00000049130
KO:
mmu:12273
|
| Nucleutide sequences |
EMBL-CDS:
AAI25642.1,
AAI25644.1,
AAB97774.1,
AAP50849.1,
BAE34324.1
Ensembl_TRS:
ENSMUST00000168818,
ENSMUST00000050770
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129972,
ENSMUSP00000060003
RefSeq:
NP_031603.2,
NP_001167021.1
|
| Others |
UniRef100:
UniRef100_P30993
UniRef90:
UniRef90_P30993
UniRef50:
UniRef50_P21730
UniGene:
Mm.247623
CCDS:
CCDS20846.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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