| Type | Description |
|---|---|
| Definition | class II transactivator |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 10:38:00 | results uncover an NFAT5-regulated mechanism that maintains CIITA and MHCII expression in macrophages and thus modulates their T lymphocyte priming capacity. | 30327417 |
| 2019-03-09 10:13:00 | Low CIITA expression is associated with cancer. | 29238041 |
| 2018-12-01 10:04:00 | This study provided evidence that CIITA is required for alpha-syn-induced MHCII expression and subsequent infiltration of peripheral immune cells in to the midbrain. | 30165873 |
| 2017-10-21 11:20:00 | study found that CIITA exerts a highly restricted control over only the MHCII, H2-DO and H2-DM genes, in DC1 and DC2 cDC subsets, but not over other proposed targets | 28608405 |
| 2017-08-26 12:51:00 | Decreasing CIITA expression in allogeneic MSCs abolished MHC II induction during myogenic differentiation and prevented immunorejection of these cells from the infarcted myocardium, which enhanced beneficial functional effects of MSC implantation on myocardial repair. | 27221978 |
| Type | IDs |
|---|---|
| Synonymous | C2ta, EG669998, Gm9475, Mhc2ta |
| Gene |
UniProtKB-ID:
C2TA_MOUSE,
Q3UU40_MOUSE,
Q8HW99_MOUSE,
Q3UNW8_MOUSE,
A0A2R8VHC7_MOUSE,
Q3KNE0_MOUSE,
Q3U5G4_MOUSE
UniprotKB:
P79621,
Q3UU40,
Q8HW99,
Q3UNW8,
A0A2R8VHC7,
Q3KNE0,
Q3U5G4
UniParc:
UPI000008B05E,
UPI00005ABE6F,
UPI00005AC265,
UPI0000027A2E,
UPI00001939CE,
UPI000002A23D,
UPI00005C3FF8,
UPI0000027138
EMBL:
AF042158,
AF042159,
AK040723,
AF100710,
AK153609,
U60653,
AF000007,
AK143956,
AF000006,
BC107330,
AC122352,
U46562,
AK138822,
AF100709
Ensembl:
ENSMUSG00000022504
KO:
mmu:12265
|
| Nucleutide sequences |
EMBL-CDS:
AAB92364.2,
AAB48859.1,
AAC34366.1,
AAF06839.1,
AAB92365.1,
AAF06838.1,
AAB05004.1,
AAC34367.1,
BAE23789.1,
BAC30683.1,
BAE25629.1,
AAI07331.1,
BAE32115.1
Ensembl_TRS:
ENSMUST00000230450,
ENSMUST00000230395,
ENSMUST00000023147,
ENSMUST00000230146
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000155002,
ENSMUSP00000155517,
ENSMUSP00000023147,
ENSMUSP00000154946
RefSeq:
XP_011244112.1,
NP_001230690.1,
XP_006521789.1,
XP_036015649.1,
XP_006521787.1,
NP_001230689.1,
NP_031601.1,
NP_001289547.1,
NP_001289548.1
|
| Others |
UniRef100:
UniRef100_Q3UNW8,
UniRef100_Q3UU40,
UniRef100_A0A2R8VHC7,
UniRef100_Q8HW99,
UniRef100_Q3KNE0,
UniRef100_P79621,
UniRef100_Q3U5G4
UniRef90:
UniRef90_Q3KNE0,
UniRef90_P79621
UniRef50:
UniRef50_P33076,
UniRef50_Q3KNE0
UniGene:
Mm.249560
CCDS:
CCDS88877.1,
CCDS88875.1,
CCDS27950.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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