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12261 C1qbp

12261

C1qbp

complement component 1, q subcomponent binding protein

protein-coding

Mus musculus

基因描述

Type Description
Definition complement component 1, q subcomponent binding protein

研究结论

Date Results Publications
2020-12-19 13:38:00 p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis. 32606429
2020-06-27 10:31:00 Arginase II activity-dependent production of spermine augments Ca(2+) transition from the cytosol to the mitochondria in a mitochondrial p32 protein -dependent manner and regulates CaMKII-dependent constriction in vascular smooth muscle cells. 31155612
2019-12-14 12:35:00 Dendritic cell maturation is regulated by citrate production via p32-dependent pyruvate dehydrogenase [PDH] complex activity. 30428349
2019-07-13 12:33:00 Here, we found that mice lacking p32 in the central nervous system (p32cKO mice) showed white matter degeneration accompanied by progressive oligodendrocyte loss, axon degeneration and vacuolation in the mid brain and brain stem regions. Furthermore, p32cKO mice died within 8 weeks of birth. 29123152
2019-02-23 10:41:00 Data show that p32 (C1QBP) plays a critical role in energy homeostasis and represents a potential target for the development of anti-obesity drugs 28720899

名称对应

Type IDs
Synonymous AA407365, AA986492, D11Wsu182e, HABP1, P32, gC1qBP
Gene
UniProtKB-ID: Q8R5L1_MOUSE
UniprotKB: Q8R5L1
UniParc: UPI00000215D5
EMBL: BC038075, AF300619, AL596136
Ensembl: ENSMUSG00000018446
KO: mmu:12261
Nucleutide sequences
EMBL-CDS: AAL77246.1, AAH38075.1
Ensembl_TRS: ENSMUST00000078528
Protein sequencees
Ensembl_PRO: ENSMUSP00000077612
RefSeq: NP_031599.2
Others
UniRef100: UniRef100_Q8R5L1
UniRef90: UniRef90_O35658
UniRef50: UniRef50_O35658
UniGene: Mm.30049

全选

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研究热度

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