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122481 AK7

122481

AK7

adenylate kinase 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition adenylate kinase 7

研究结论

Date Results Publications
2020-05-23 12:50:00 The mRNA and protein expressions of AK1, AK6 and AK7 are significantly down-regulated in the sperm of asthenospermia patients, which may be closely related with reduced sperm motility. 32251557
2019-02-02 12:05:00 a novel genetic cause of asthenozoospermia due to MMAF and suggests that in humans, more deleterious mutations of AK7 might induce primary ciliary dyskinesia. 29365104
2012-12-22 10:09:00 AK7 may be involved in the development of Primary ciliary dyskinesia (PCD). 22801010
2011-02-26 10:37:00 Both AK7 and full-length AK8 showed highest affinity for AMP with ATP as the phosphate donor, and proved to be more efficient in AMP phosphorylation as compared with the major cytosolic isoform AK1 21080915
2010-11-27 10:09:00 expression is decreased in patients with primary ciliary dyskinesia and is correlated with ciliary beat frequency of nasal epithelium cellsepithelium 20537283

名称对应

Type IDs
Synonymous AK 7, SPGF27
Gene
UniProtKB-ID: KAD7_HUMAN
UniprotKB: Q96M32
UniParc: UPI00001FDB1D
EMBL: AL163051, AK057426, AL359240
Ensembl: ENSG00000140057
KO: hsa:122481
Nucleutide sequences
EMBL-CDS: BAB71480.1
Ensembl_TRS: ENST00000267584
Protein sequencees
Ensembl_PRO: ENSP00000267584
RefSeq: NP_001337817.1, XP_006720084.1, XP_006720085.1, NP_689540.2, XP_016876447.1, NP_001337819.1, NP_001337821.1, NP_001337820.1, XP_016876449.1
Others
UniRef100: UniRef100_Q96M32
UniRef90: UniRef90_Q96M32
UniRef50: UniRef50_Q96M32
UniGene: Hs.667462
CCDS: CCDS9945.1

全选

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研究热度

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