| Type | Description |
|---|---|
| Definition | ankyrin repeat domain 9 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:19:00 | ANKRD9 regulates IMPDH2 abundance and macro-assembly in response to metabolic changes. | 31337707 |
| 2019-05-25 12:28:00 | show that ANKRD9 is genetically and functionally associated with tumor suppression by acting as a substrate receptor subunit of a CUL5-based E3 ubiquitin ligase that ubiquitinates substrate proteins as IMPDH2 and presumably IMPDH1, marking them for proteasomal degradation and turnover. Furthermore, ANKRD9 accomplishes its anti-proliferative and tumor-suppressive function via IMPDH2 degradation. | 30293565 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ANKR9_HUMAN
UniprotKB:
Q96BM1
UniParc:
UPI000000CC75
EMBL:
BX161460,
AL136293,
BC015422,
AK291868,
CH471061,
BC027479
Ensembl:
ENSG00000156381
KO:
hsa:122416
|
| Nucleutide sequences |
EMBL-CDS:
CAD61921.1,
BAF84557.1,
AAH15422.1,
EAW81792.1,
AAH27479.1
Ensembl_TRS:
ENST00000559651,
ENST00000560748,
ENST00000286918
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000286918,
ENSP00000454100,
ENSP00000453650
RefSeq:
NP_001335580.1,
NP_689539.1,
XP_005267367.1,
NP_001335581.1
|
| Others |
UniRef100:
UniRef100_Q96BM1
UniRef90:
UniRef90_Q96BM1
UniRef50:
UniRef50_Q96BM1
UniGene:
Hs.432945
CCDS:
CCDS9973.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31337707 |
ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly. J Biol Chem Dawn Hayward , Valentina L Kouznetsova , Hannah E Pierson , Nesrin M Hasan , Estefany R Guzman , Igor F Tsigelny , Svetlana Lutsenko |
2019-09-27 | - |
| 31387940 |
BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress. J Cell Biol Fei-Yun Chen , Min-Yu Huang , Yu-Min Lin , Chi-Huan Ho , Shu-Yu Lin , Hsin-Yi Chen , Mien-Chie Hung , Ruey-Hwa Chen |
2019-09-02 | - |
| 30293565 |
ANKRD9 is associated with tumor suppression as a substrate receptor subunit of ubiquitin ligase. Biochim Biophys Acta Mol Basis Dis Yejin Lee , Byungho Lim , Seon Woo Lee , Woo Rin Lee , Yong-In Kim , Minhyeok Kim , Hyoungseok Ju , Mi Young Kim , Suk-Jo Kang , Ji-Joon Song , J Eugene Lee , Changwon Kang |
2018-10-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24952745 |
Nat. Genet. Dan E Arking , Sara L Pulit , Lia Crotti , Pim van der Harst , Patricia B Munroe , Tamara T Koopmann , Nona Sotoodehnia , Elizabeth J Rossin , Michael Morley , Xinchen Wang , Andrew D Johnson , Alicia Lundby , DanÃel F Gudbjartsson , Peter A Noseworthy , Mark Eijgelsheim , Yuki Bradford , Kirill V Tarasov , Marcus Dörr , Martina Müller-Nurasyid , Annukka M Lahtinen , Ilja M Nolte , Albert Vernon Smith , Joshua C Bis , Aaron Isaacs , Stephen J Newhouse , Daniel S Evans , Wendy S Post , Daryl Waggott , Leo-Pekka Lyytikäinen , Andrew A Hicks , Lewin Eisele , David Ellinghaus , Caroline Hayward , Pau Navarro , Sheila Ulivi , Toshiko Tanaka , David J Tester , Stéphanie Chatel , Stefan Gustafsson , Meena Kumari , Richard W Morris , à sa T Naluai , Sandosh Padmanabhan , Alexander Kluttig , Bernhard Strohmer , Andrie G Panayiotou , Maria Torres , Michael Knoflach , Jaroslav A Hubacek , Kamil Slowikowski , Soumya Raychaudhuri , Runjun D Kumar , Tamara B Harris , Lenore J Launer , Alan R Shuldiner , Alvaro Alonso , Joel S Bader , Georg Ehret , Hailiang Huang , W H Linda Kao , James B Strait , Peter W Macfarlane , Morris Brown , Mark J Caulfield , Nilesh J Samani , Florian Kronenberg , Johann Willeit , CARe Consortium , COGENT Consortium , J Gustav Smith , Karin H Greiser , Henriette Meyer Zu Schwabedissen , Karl Werdan , Massimo Carella , Leopoldo Zelante , Susan R Heckbert , Bruce M Psaty , Jerome I Rotter , Ivana Kolcic , Ozren PolaÅ¡ek , Alan F Wright , Maura Griffin , Mark J Daly , DCCT/EDIC , David O Arnar , Hilma Hólm , Unnur Thorsteinsdottir , eMERGE Consortium , Joshua C Denny , Dan M Roden , Rebecca L Zuvich , Valur Emilsson , Andrew S Plump , Martin G Larson , Christopher J O'Donnell , Xiaoyan Yin , Marco Bobbo , Adamo P D'Adamo , Annamaria Iorio , Gianfranco Sinagra , Angel Carracedo , Steven R Cummings , Michael A Nalls , Antti Jula , Kimmo K Kontula , Annukka Marjamaa , Lasse Oikarinen , Markus Perola , Kimmo Porthan , Raimund Erbel , Per Hoffmann , Karl-Heinz Jöckel , Hagen Kälsch , Markus M Nöthen , HRGEN Consortium , Marcel den Hoed , Ruth J F Loos , Dag S Thelle , Christian Gieger , Thomas Meitinger , Siegfried Perz , Annette Peters , Hanna Prucha , Moritz F Sinner , Melanie Waldenberger , Rudolf A de Boer , Lude Franke , Pieter A van der Vleuten , Britt Maria Beckmann , Eimo Martens , Abdennasser Bardai , Nynke Hofman , Arthur A M Wilde , Elijah R Behr , Chrysoula Dalageorgou , John R Giudicessi , Argelia Medeiros-Domingo , Julien Barc , Florence Kyndt , Vincent Probst , Alice Ghidoni , Roberto Insolia , Robert M Hamilton , Stephen W Scherer , Jeffrey Brandimarto , Kenneth Margulies , Christine E Moravec , Fabiola del Greco M , Christian Fuchsberger , Jeffrey R O'Connell , Wai K Lee , Graham C M Watt , Harry Campbell , Sarah H Wild , Nour E El Mokhtari , Norbert Frey , Folkert W Asselbergs , Irene Mateo Leach , Gerjan Navis , Maarten P van den Berg , Dirk J van Veldhuisen , Manolis Kellis , Bouwe P Krijthe , Oscar H Franco , Albert Hofman , Jan A Kors , André G Uitterlinden , Jacqueline C M Witteman , Lyudmyla Kedenko , Claudia Lamina , Ben A Oostra , Gonçalo R Abecasis , Edward G Lakatta , Antonella Mulas , Marco Orrú , David Schlessinger , Manuela Uda , Marcello R P Markus , Uwe Völker , Harold Snieder , Timothy D Spector , Johan Ãrnlöv , Lars Lind , Johan Sundström , Ann-Christine Syvänen , Mika Kivimaki , Mika Kähönen , Nina Mononen , Olli T Raitakari , Jorma S Viikari , Vera Adamkova , Stefan Kiechl , Maria Brion , Andrew N Nicolaides , Bernhard Paulweber , Johannes Haerting , Anna F Dominiczak , Fredrik Nyberg , Peter H Whincup , Aroon D Hingorani , Jean-Jacques Schott , Connie R Bezzina , Erik Ingelsson , Luigi Ferrucci , Paolo Gasparini , James F Wilson , Igor Rudan , Andre Franke , Thomas W Mühleisen , Peter P Pramstaller , Terho J Lehtimäki , Andrew D Paterson , Afshin Parsa , Yongmei Liu , Cornelia M van Duijn , David S Siscovick , Vilmundur Gudnason , Yalda Jamshidi , Veikko Salomaa , Stephan B Felix , Serena Sanna , Marylyn D Ritchie , Bruno H Stricker , Kari Stefansson , Laurie A Boyer , Thomas P Cappola , Jesper V Olsen , Kasper Lage , Peter J Schwartz , Stefan Kääb , Aravinda Chakravarti , Michael J Ackerman , Arne Pfeufer , Paul I W de Bakker , Christopher Newton-Cheh |
2014-08-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 18187620 |
Identification of host proteins required for HIV infection through a functional genomic screen. Science Abraham L Brass , Derek M Dykxhoorn , Yair Benita , Nan Yan , Alan Engelman , Ramnik J Xavier , Judy Lieberman , Stephen J Elledge |
2008-02-15 |
gag,
gag-pol,
vif,
vpr,
tat,
rev,
vpu,
env,
nef,
MED6,
PIGK,
HUWE1,
PDIA6,
MPHOSPH6,
ADAM10,
RABEPK,
RRAGB,
ATG7,
ARPC1A,
POLR3F,
LEFTY1,
PNRC1,
TMED2,
PRDM7,
POLR3A,
ERI2,
SLC46A1,
SFT2D1,
GABARAPL2,
CARD16,
PKD1L2,
XKR4,
AGAP2,
AP2M1,
CLN3,
CLNS1A,
ERP27,
ANKRD9,
ZNF720,
RPTN,
ARHGEF19,
ZNF831,
C4orf33,
SOWAHA,
C9orf131,
RIMS4,
FAM76B,
ZNF785,
LYPD4,
PM20D1,
IQUB,
ZNF791,
DDOST,
DDX3X,
DMXL1,
DDX10,
TIMM8A,
DDX53,
EDNRA,
AGO3,
EGF,
EGFR,
CRTC2,
EPS8,
ERCC3,
AKT1,
AKT2,
ETF1,
DOK6,
C6orf1,
LNX2,
FHL3,
COG2,
TRAPPC8,
ANKRD6,
BAHD1,
FBXO21,
WDTC1,
FLII,
SEPT8,
MDN1,
OTUD3,
SCFD1,
NUP160,
FBXW11,
ARHGEF12,
FNTA,
PIP5K1C,
PHF3,
ETHE1,
TNPO3,
KLHDC2,
MKRN2,
COG4,
TRIM58,
INTS7,
SPATS2L,
GAPVD1,
RSL1D1
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12508121 |
The DNA sequence and analysis of human chromosome 14. Nature Roland Heilig , Ralph Eckenberg , Jean-Louis Petit , Núria Fonknechten , Corinne Da Silva , Laurence Cattolico , Michaël Levy , Valérie Barbe , Véronique de Berardinis , Abel Ureta-Vidal , Eric Pelletier , Virginie Vico , Véronique Anthouard , Lee Rowen , Anup Madan , Shizhen Qin , Hui Sun , Hui Du , Kymberlie Pepin , François Artiguenave , Catherine Robert , Corinne Cruaud , Thomas Brüls , Olivier Jaillon , Lucie Friedlander , Gaelle Samson , Philippe Brottier , Susan Cure , Béatrice Ségurens , Franck Anière , Sylvie Samain , Hervé Crespeau , Nissa Abbasi , Nathalie Aiach , Didier Boscus , Rachel Dickhoff , Monica Dors , Ivan Dubois , Cynthia Friedman , Michel Gouyvenoux , Rose James , Anuradha Madan , Barbara Mairey-Estrada , Sophie Mangenot , Nathalie Martins , Manuela Ménard , Sophie Oztas , Amber Ratcliffe , Tristan Shaffer , Barbara Trask , Benoit Vacherie , Chadia Bellemere , Caroline Belser , Marielle Besnard-Gonnet , Delphine Bartol-Mavel , Magali Boutard , Stéphanie Briez-Silla , Stephane Combette , Virginie Dufossé-Laurent , Carolyne Ferron , Christophe Lechaplais , Claudine Louesse , Delphine Muselet , Ghislaine Magdelenat , Emilie Pateau , Emmanuelle Petit , Peggy Sirvain-Trukniewicz , Arnaud Trybou , Nathalie Vega-Czarny , Elodie Bataille , Elodie Bluet , Isabelle Bordelais , Maria Dubois , Corinne Dumont , Thomas Guérin , Sébastien Haffray , Rachid Hammadi , Jacqueline Muanga , Virginie Pellouin , Dominique Robert , Edith Wunderle , Gilbert Gauguet , Alice Roy , Laurent Sainte-Marthe , Jean Verdier , Claude Verdier-Discala , LaDeana Hillier , Lucinda Fulton , John McPherson , Fumihiko Matsuda , Richard Wilson , Claude Scarpelli , Gábor Gyapay , Patrick Wincker , William Saurin , Francis Quétier , Robert Waterston , Leroy Hood , Jean Weissenbach |
2003-02-06 |
LOC100132257,
NF1P4,
RRAGAP1,
RNF212B,
SEC23A,
BATF,
AHSA1,
TMED10,
FERMT2,
FOXN3,
C14orf1,
IFT43,
ANKRD9,
AK7,
C14orf79,
FRMD6,
GPHB5,
NOXRED1,
TTC7B,
SYNE3,
CLEC14A,
MDGA2,
SAMD15,
NOP9,
ESRRB,
VASH1,
FOXG1,
SNW1,
PCNX1,
DAAM1,
TTLL5,
SYNE2,
ANGEL1,
PPP1R13B,
RHOQ,
FOS,
NUDT14,
SIPA1L1,
TMED8,
OR4K3,
CEP170B,
FOXN3-AS2,
STXBP6,
GSTZ1,
GTF2A1,
POMT2,
DHRS4L2,
CCDC85C,
VSX2,
RAB15,
RTL1,
TMEM179,
KTN1,
OR11H7,
RNASE9,
PLEKHD1,
LTBP2,
ATL1,
FCF1,
DACT1,
GSKIP,
DHRS7,
PGF,
ZFYVE1,
NRDE2,
ATG2B,
RBM23,
DNAAF2,
FLVCR2,
TDP1,
SPATA7,
YLPM1,
METTL3,
PSEN1,
TMEM63C,
ADAMTSL3,
NGB,
RBM25,
RAD51B,
VIPAS39,
SMOC1,
POTEM,
IRF2BPL,
NF1P6,
TGFB3,
DHRS4L1,
CCDC175,
OTUB2,
THTPA,
CLMN,
RIN3,
DCAF11,
CALM3,
SGPP1,
TMX1,
RPS6KL1,
GPR65,
STON2,
ALKBH1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员