| Type | Description |
|---|---|
| Definition | beta-transducin repeat containing protein |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 11:54:00 | Results show that mono-ADP-ribosylates beta-TrCP which promotes IFNAR1 ubiquitination and degradation. | 30988430 |
| 2019-10-26 10:25:00 | Study findings identify beta-TrCP as an important negative regulator for upstream signaling of IkappaBalpha in lipopolysaccharide pathway, and therefore renew the understanding of the roles of beta-TrCP in regulating toll-like receptors inflammatory signaling. | 30619291 |
| 2019-08-03 11:46:00 | Investigated beta-TrCP function in Sertoli cells by generating mice with targeted deletion of the beta-TrCP2 gene in Sertoli cells on a background of whole-body beta-TrCP1 knockout. Loss of beta-TrCP in Sertoli cells caused infertility due to a reduction in the number of mature sperm. | 30391586 |
| 2019-01-09 15:29:00 | beta-TrCP was identified as a novel interacting partner of ASK1 that is capable of ubiquitinating and degrading ASK1 through the ubiquitin-proteasome system. These findings suggest that beta-TrCP is capable of suppressing oxidative stress-induced caspase 3-dependent apoptosis through suppression of ASK1. | 30031111 |
| 2017-12-02 11:06:00 | beta-TrCP regulates the transition from mitosis to meiosis in male germ cells by targeting DMRT1 for degradation. | 28982686 |
| Type | IDs |
|---|---|
| Synonymous | Beta-Trcp1, E3RS-IkappaB, E3RSIkappaB, FWD1, Fbw1a, HOS, SCF b-TRCP, Slimb, b-TrCP, beta-TrCP |
| Gene |
UniProtKB-ID:
FBW1A_MOUSE,
A0A286YDT6_MOUSE
UniprotKB:
Q3ULA2,
A0A286YDT6
UniParc:
UPI00002161AA,
UPI00000298CD,
UPI00004CB41E
EMBL:
AF391182,
AK145624,
AF391181,
BC003989,
AF391187,
AF391185,
AK220183,
AF391186,
AF391188,
AC126454,
AF391180,
AF081887,
AF391183,
AF099932,
AK156660,
AF391184,
AF112979,
AC123058,
AF391189,
CH466534,
AF110396,
AF391179,
AF391190,
AF391178
Ensembl:
ENSMUSG00000025217
KO:
mmu:12234
|
| Nucleutide sequences |
EMBL-CDS:
EDL41951.1,
BAE26547.1,
AAD08701.1,
AAD17755.1,
BAD90368.1,
AAD41025.1,
AAH03989.1,
AAD04181.1,
AAL40929.1,
BAE33798.1
Ensembl_TRS:
ENSMUST00000111936,
ENSMUST00000065601,
ENSMUST00000224478
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000070728,
ENSMUSP00000107567,
ENSMUSP00000153562
RefSeq:
NP_001347049.1,
XP_030106576.1,
XP_006526676.1,
XP_006526678.1,
XP_030106575.1,
XP_030106571.1,
XP_030106572.1,
XP_036017304.1,
XP_030106581.1,
NP_001273395.1,
XP_036017300.1,
NP_001347056.1,
XP_006526675.1,
XP_036017299.1,
XP_011245425.1,
XP_030106582.1,
XP_011245422.1,
XP_036017302.1,
NP_001347051.1,
XP_036017301.1,
XP_030106573.1,
XP_011245421.1,
NP_033901.1,
NP_001347055.1,
XP_030106578.1,
XP_006526677.2,
XP_036017298.1,
XP_036017306.1,
NP_001273394.1,
NP_001347053.1,
XP_030106579.1,
XP_036017305.1,
NP_001032847.2,
XP_011245429.1,
XP_030106574.1,
XP_030106580.1,
XP_036017303.1,
XP_011245423.1
|
| Others |
UniRef100:
UniRef100_A0A286YDT6,
UniRef100_Q3ULA2
UniRef90:
UniRef90_Q9Y297
UniRef50:
UniRef50_Q9Y297
UniGene:
Mm.119717,
Mm.446448
CCDS:
CCDS38002.1,
CCDS29860.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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