| Type | Description |
|---|---|
| Definition | betacellulin, epidermal growth factor family member |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 10:21:00 | the results of the current study provided validation suggesting that the downregulation of miR-149 confers protection to retinal ganglion cells (RGCs) by means of activating the PI3K/Akt signaling pathway via upregulation of betacellulin in mice with glaucoma. Evidence presented indicated the promise of miR-149 inhibition as a potential therapeutic strategy for glaucoma treatment. | 30183321 |
| 2018-02-17 10:32:00 | Betacellulin promotes the proliferation of corneal epithelial stem cells through the phosphorylation of Erk1/Erk2. | 29331377 |
| 2018-01-13 13:38:00 | The results of this study suggested a novel regulatory role of Btc in axon-Schwann cell interactions involved in myelin formation and nerve repair. | 28139851 |
| 2012-03-31 10:05:00 | BTC induces expansion of neural stem cells and neuroblasts, and promotes neurogenesis in the olfactory bulb and dentate gyrus. | 22232668 |
| 2011-12-24 10:04:00 | Betacellulin exerts proliferative activity on beta cells through the activation of ErbB-1 and ErbB-2 receptors | 21897861 |
| Type | IDs |
|---|---|
| Synonymous | Bcn |
| Gene |
UniProtKB-ID:
BTC_MOUSE,
Q543J8_MOUSE,
Q3TP84_MOUSE
UniprotKB:
Q05928,
Q543J8,
Q3TP84
UniParc:
UPI000000130D,
UPI00005B20A7
EMBL:
BC119154,
AK076272,
AK050206,
AF368019,
AF368018,
L08394,
BC119152,
AF368017,
AK164633,
AH011612
Ensembl:
ENSMUSG00000082361
KO:
mmu:12223
|
| Nucleutide sequences |
EMBL-CDS:
AAA40511.1,
BAC36281.1,
BAC34122.1,
AAI19153.1,
AAI19155.1,
AAM21214.1,
BAE37853.1
Ensembl_TRS:
ENSMUST00000121044
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112765
RefSeq:
NP_031594.1
|
| Others |
UniRef100:
UniRef100_Q05928
UniRef90:
UniRef90_Q05928
UniRef50:
UniRef50_P35070
UniGene:
Mm.2024
CCDS:
CCDS19422.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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