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The mutational constraint spectrum quantified from variation in 141,456 humans.

Nature     Konrad J Karczewski , Laurent C Francioli , Grace Tiao , Beryl B Cummings , Jessica Alföldi , Qingbo Wang , Ryan L Collins , Kristen M Laricchia , Andrea Ganna , Daniel P Birnbaum , Laura D Gauthier , Harrison Brand , Matthew Solomonson , Nicholas A Watts , Daniel Rhodes , Moriel Singer-Berk , Eleina M England , Eleanor G Seaby , Jack A Kosmicki , Raymond K Walters , Katherine Tashman , Yossi Farjoun , Eric Banks , Timothy Poterba , Arcturus Wang , Cotton Seed , Nicola Whiffin , Jessica X Chong , Kaitlin E Samocha , Emma Pierce-Hoffman , Zachary Zappala , Anne H O'Donnell-Luria , Eric Vallabh Minikel , Ben Weisburd , Monkol Lek , James S Ware , Christopher Vittal , Irina M Armean , Louis Bergelson , Kristian Cibulskis , Kristen M Connolly , Miguel Covarrubias , Stacey Donnelly , Steven Ferriera , Stacey Gabriel , Jeff Gentry , Namrata Gupta , Thibault Jeandet , Diane Kaplan , Christopher Llanwarne , Ruchi Munshi , Sam Novod , Nikelle Petrillo , David Roazen , Valentin Ruano-Rubio , Andrea Saltzman , Molly Schleicher , Jose Soto , Kathleen Tibbetts , Charlotte Tolonen , Gordon Wade , Michael E Talkowski , Genome Aggregation Database Consortium , Benjamin M Neale , Mark J Daly , Daniel G MacArthur

Identification of a large set of rare complete human knockouts.

Nat. Genet.     Patrick Sulem , Hannes Helgason , Asmundur Oddson , Hreinn Stefansson , Sigurjon A Gudjonsson , Florian Zink , Eirikur Hjartarson , Gunnar Th Sigurdsson , Adalbjorg Jonasdottir , Aslaug Jonasdottir , Asgeir Sigurdsson , Olafur Th Magnusson , Augustine Kong , Agnar Helgason , Hilma Holm , Unnur Thorsteinsdottir , Gisli Masson , Daniel F Gudbjartsson , Kari Stefansson

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.

Genomics     Philippe Lamesch , Ning Li , Stuart Milstein , Changyu Fan , Tong Hao , Gabor Szabo , Zhenjun Hu , Kavitha Venkatesan , Graeme Bethel , Paul Martin , Jane Rogers , Stephanie Lawlor , Stuart McLaren , Amélie Dricot , Heather Borick , Michael E Cusick , Jean Vandenhaute , Ian Dunham , David E Hill , Marc Vidal

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

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The DNA sequence and analysis of human chromosome 13.

Nature     A Dunham , L H Matthews , J Burton , J L Ashurst , K L Howe , K J Ashcroft , D M Beare , D C Burford , S E Hunt , S Griffiths-Jones , M C Jones , S J Keenan , K Oliver , C E Scott , R Ainscough , J P Almeida , K D Ambrose , D T Andrews , R I S Ashwell , A K Babbage , C L Bagguley , J Bailey , R Bannerjee , K F Barlow , K Bates , H Beasley , C P Bird , S Bray-Allen , A J Brown , J Y Brown , W Burrill , C Carder , N P Carter , J C Chapman , M E Clamp , S Y Clark , G Clarke , C M Clee , S C M Clegg , V Cobley , J E Collins , N Corby , G J Coville , P Deloukas , P Dhami , I Dunham , M Dunn , M E Earthrowl , A G Ellington , L Faulkner , A G Frankish , J Frankland , L French , P Garner , J Garnett , J G R Gilbert , C J Gilson , J Ghori , D V Grafham , S M Gribble , C Griffiths , R E Hall , S Hammond , J L Harley , E A Hart , P D Heath , P J Howden , E J Huckle , P J Hunt , A R Hunt , C Johnson , D Johnson , M Kay , A M Kimberley , A King , G K Laird , C J Langford , S Lawlor , D A Leongamornlert , D M Lloyd , C Lloyd , J E Loveland , J Lovell , S Martin , M Mashreghi-Mohammadi , S J McLaren , A McMurray , S Milne , M J F Moore , T Nickerson , S A Palmer , A V Pearce , A I Peck , S Pelan , B Phillimore , K M Porter , C M Rice , S Searle , H K Sehra , R Shownkeen , C D Skuce , M Smith , C A Steward , N Sycamore , J Tester , D W Thomas , A Tracey , A Tromans , B Tubby , M Wall , J M Wallis , A P West , S L Whitehead , D L Willey , L Wilming , P W Wray , M W Wright , L Young , A Coulson , R Durbin , T Hubbard , J E Sulston , S Beck , D R Bentley , J Rogers , M T Ross

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Proc. Natl. Acad. Sci. U.S.A.     Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team