Zfp36l2 - zinc finger protein 36, C3H type-like 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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12193 Zfp36l2

基因描述

Type	Description
Definition	zinc finger protein 36, C3H type-like 2

研究结论

Date	Results	Publications
2021-04-03 13:36:00	RNA-Binding Protein ZFP36L2 Downregulates Helios Expression and Suppresses the Function of Regulatory T Cells.	32655569
2019-02-16 11:15:00	ZFP36L2 protein is expressed in satellite cells. ZFP36L1 and ZFP36L2 act redundantly in myogenesis.	30526691
2018-06-02 11:24:00	Loss of ZFP36L2 is associated with female infertility.	29408237
2017-10-07 10:11:00	The Zfp36l2 therefore act as posttranscriptional safeguards against chromosomal instability and replication stress by integrating pre-TCR and IL-7 signaling with DNA damage and cell cycle control.	27566829
2017-09-23 11:51:00	Study tested for the first time a role of ZFP36L2 in the decay of LHR mRNA, when transcription was inhibited; results of our cell-based assay support the conclusion that LHR mRNA expression is controlled post-transcriptionally by ZFP36L2.	28455422

名称对应

Type	IDs
Synonymous	Brf2, ERF2, Tis11d
Gene	UniProtKB-ID: TISD_MOUSE UniprotKB: P23949 UniParc: UPI00003B25E5 EMBL: M58564, AK170763, M97165, AC132455, BC139416, AK160955 Ensembl: ENSMUSG00000045817 KO: mmu:12193
Nucleutide sequences	EMBL-CDS: AAA72946.1, AAI39417.1, BAE36112.1, BAE42014.1, AAA39709.1 Ensembl_TRS: ENSMUST00000060366
Protein sequencees	Ensembl_PRO: ENSMUSP00000050820 RefSeq: NP_001001806.1
Others	UniRef100: UniRef100_P23949 UniRef90: UniRef90_P23949 UniRef50: UniRef50_P23949 UniGene: Mm.259321 CCDS: CCDS28998.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32655569	RNA-Binding Protein ZFP36L2 Downregulates Helios Expression and Suppresses the Function of Regulatory T Cells. Front Immunol Sohei Makita , Hiroaki Takatori , Arifumi Iwata , Shigeru Tanaka , Shunsuke Furuta , Kei Ikeda , Akira Suto , Kotaro Suzuki , Silvia B V Ramos , Hiroshi Nakajima	2020-01-01	-
31330130	Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout. Dev. Biol. Matthew R Hildebrandt , Yixiong Wang , Lei Li , Lubna Yasmin , Darryl D Glubrecht , Roseline Godbout	2019-11-15	-
30526691	The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis. Skelet Muscle Hema Bye-A-Jee , Dhamayanthi Pugazhendhi , Samuel Woodhouse , Patrick Brien , Rachel Watson , Martin Turner , Jennifer Pell	2018-12-07	-
29988089	Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells. Nat Immunol Fiamma Salerno , Sander Engels , Maartje van den Biggelaar , Floris P J van Alphen , Aurelie Guislain , Wanqi Zhao , Deborah L Hodge , Sarah E Bell , Jan Paul Medema , Marieke von Lindern , Martin Turner , Howard A Young , Monika C Wolkers	2018-08-01	-
29408237	Chromatin Modification and Global Transcriptional Silencing in the Oocyte Mediated by the mRNA Decay Activator ZFP36L2. Dev. Cell Jennifer N Dumdie , Kyucheol Cho , Madhuvanthi Ramaiah , David Skarbrevik , Sergio Mora-Castilla , Deborah J Stumpo , Jens Lykke-Andersen , Louise C Laurent , Perry J Blackshear , Miles F Wilkinson , Heidi Cook-Andersen	2018-02-05	-
28455422	Impact of RNA structure on ZFP36L2 interaction with luteinizing hormone receptor mRNA. RNA Christopher B Ball , Amanda C Solem , Rita M Meganck , Alain Laederach , Silvia B V Ramos	2017-08-01	-
28394372	Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1. Nat Immunol Rebecca Newman , Helena Ahlfors , Alexander Saveliev , Alison Galloway , Daniel J Hodson , Robert Williams , Gurdyal S Besra , Charlotte N Cook , Adam F Cunningham , Sarah E Bell , Martin Turner	2017-06-01	-
27566829	The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic Î²-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression. J. Immunol. Katharina U Vogel , Lewis S Bell , Alison Galloway , Helena Ahlfors , Martin Turner	2016-10-01	-
27102483	RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science Alison Galloway , Alexander Saveliev , Sebastian Åukasiak , Daniel J Hodson , Daniel Bolland , Kathryn Balmanno , Helena Ahlfors , Elisa MonzÃ³n-Casanova , Sara Ciullini Mannurita , Lewis S Bell , Simon Andrews , Manuel D DÃaz-MuÃ±oz , Simon J Cook , Anne Corcoran , Martin Turner	2016-04-22	-
26952984	Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism. Development Deborah J Stumpo , Carol S Trempus , Charles J Tucker , Weichun Huang , Leping Li , Kimberly Kluckman , Donna M Bortner , Perry J Blackshear	2016-04-15	-

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