Zfp36l1 - zinc finger protein 36, C3H type-like 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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12192 Zfp36l1

基因描述

Type	Description
Definition	zinc finger protein 36, C3H type-like 1

研究结论

Date	Results	Publications
2020-10-03 12:54:00	Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.	30858608
2019-02-23 13:15:00	Study shows that the ZFP36 family member, ZFP36L1, is specifically upregulated in osteoarthritis (OA) chondrocytes and OA cartilage of humans and mice. ZFP36L1 regulates the mRNAs encoding two members of the HSP70 family that appear to exert protective effects on OA pathogenesis by inhibiting chondrocyte apoptosis.	30622281
2019-02-16 11:15:00	ZFP36L1 protein is expressed in satellite cells. ZFP36L1 and ZFP36L2 act redundantly in myogenesis.	30526691
2017-10-21 12:24:00	the ZFP36L1-dependent regulation of bile acid metabolism is an important metabolic contributor to obesity and hepatosteatosis.	28891815
2017-10-07 10:11:00	The Zfp36l1 therefore act as posttranscriptional safeguards against chromosomal instability and replication stress by integrating pre-TCR and IL-7 signaling with DNA damage and cell cycle control.	27566829

名称对应

Type	IDs
Synonymous	AW742437, AW743212, Berg36, Brf1, D530020L18Rik, ERF1, TIS11b, cMG1
Gene	UniProtKB-ID: TISB_MOUSE, Q543H2_MOUSE UniprotKB: P23950, Q543H2 UniParc: UPI0000003FFE EMBL: AK051035, M58566, AK036950 Ensembl: ENSMUSG00000021127 KO: mmu:12192
Nucleutide sequences	EMBL-CDS: AAA72948.1, BAC29648.1, BAC34506.1 Ensembl_TRS: ENSMUST00000021552, ENSMUST00000165114
Protein sequencees	Ensembl_PRO: ENSMUSP00000127522, ENSMUSP00000021552 RefSeq: NP_031590.1
Others	UniRef100: UniRef100_P23950 UniRef90: UniRef90_Q07352 UniRef50: UniRef50_Q07352 UniGene: Mm.235132 CCDS: CCDS26010.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
30858608	Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas. Cell Death Differ Dritan Liko , Louise Mitchell , Kirsteen J Campbell , Rachel A Ridgway , Carolyn Jones , Kate Dudek , Ayala King , Sheila Bryson , David Stevenson , Karen Blyth , Douglas Strathdee , Jennifer P Morton , Thomas G Bird , John R P Knight , Anne E Willis , Owen J Sansom	2019-12-01	-
30622281	RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family. Nat Commun Young-Ok Son , Hyo-Eun Kim , Wan-Su Choi , Churl-Hong Chun , Jang-Soo Chun	2019-01-08	-
30526691	The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis. Skelet Muscle Hema Bye-A-Jee , Dhamayanthi Pugazhendhi , Samuel Woodhouse , Patrick Brien , Rachel Watson , Martin Turner , Jennifer Pell	2018-12-07	-
29513653	Developmental diversification of cortical inhibitory interneurons. Nature Christian Mayer , Christoph Hafemeister , Rachel C Bandler , Robert Machold , Renata Batista Brito , Xavier Jaglin , Kathryn Allaway , Andrew Butler , Gord Fishell , Rahul Satija	2018-03-22	-
28891815	RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism. J. Clin. Invest. Elizabeth J Tarling , Bethan L Clifford , Joan Cheng , Pauline Morand , Angela Cheng , Ellen Lester , Tamer Sallam , Martin Turner , Thomas Q de Aguiar Vallim	2017-10-02	-
28394372	Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1. Nat Immunol Rebecca Newman , Helena Ahlfors , Alexander Saveliev , Alison Galloway , Daniel J Hodson , Robert Williams , Gurdyal S Besra , Charlotte N Cook , Adam F Cunningham , Sarah E Bell , Martin Turner	2017-06-01	-
28206953	Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells. Oncotarget Kuo-Yun Tseng , Yi-Hsuan Chen , Shankung Lin	2017-03-28	-
27566829	The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic Î²-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression. J. Immunol. Katharina U Vogel , Lewis S Bell , Alison Galloway , Helena Ahlfors , Martin Turner	2016-10-01	-
27102483	RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science Alison Galloway , Alexander Saveliev , Sebastian Åukasiak , Daniel J Hodson , Daniel Bolland , Kathryn Balmanno , Helena Ahlfors , Elisa MonzÃ³n-Casanova , Sara Ciullini Mannurita , Lewis S Bell , Simon Andrews , Manuel D DÃaz-MuÃ±oz , Simon J Cook , Anne Corcoran , Martin Turner	2016-04-22	-
26952984	Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism. Development Deborah J Stumpo , Carol S Trempus , Charles J Tucker , Weichun Huang , Leping Li , Kimberly Kluckman , Donna M Bortner , Perry J Blackshear	2016-04-15	-

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