| Type | Description |
|---|---|
| Definition | SET and MYND domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:27:00 | Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1. | 32574189 |
| 2019-04-06 10:19:00 | The data suggest that skNAC and Smyd1 might be major players in the processes of myofibrillogenesis and sarcomerogenesis, probably specifically at later stages. | 29499397 |
| 2018-10-06 11:02:00 | These findings provide functional evidence for a role of Smyd1, or any member of the Smyd family, in regulating cardiac energetics in the adult heart, which is mediated, at least in part, via modulating PGC-1alpha. | 30061404 |
| 2017-07-01 11:33:00 | Smyd1 is responsible for restricting growth in the adult heart, with its absence leading to cellular hypertrophy, organ remodeling, and fulminate heart failure. Molecular studies reveal Smyd1 to be a muscle-specific regulator of gene expression and indicate that Smyd1 modulates expression of gene isoforms whose expression is associated with cardiac pathology. Activation of Smyd1 can prevent pathological cell growth. | 27663768 |
| 2016-12-17 11:01:00 | This work illustrates a crucial role for SMYD1 in skeletal muscle physiology and myofibril integrity. | 26935107 |
| Type | IDs |
|---|---|
| Synonymous | 4632404M21Rik, Bop, C78565, Zmynd18 |
| Gene |
UniProtKB-ID:
SMYD1_MOUSE,
Q3UQT9_MOUSE
UniprotKB:
P97443,
Q3UQT9
UniParc:
UPI00003BF2CB,
UPI00005AC0F7,
UPI00020530B5
EMBL:
U76374,
U76373,
AK142153,
U76371,
AK142252,
CH466523,
BC076601
Ensembl:
ENSMUSG00000055027
KO:
mmu:12180
|
| Nucleutide sequences |
EMBL-CDS:
BAE24995.1,
AAC53021.2,
AAC53022.2,
AAC53020.1,
AAH76601.1,
EDK98934.1,
BAE24950.1
Ensembl_TRS:
ENSMUST00000074301,
ENSMUST00000114186
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109824,
ENSMUSP00000073911
RefSeq:
NP_001153599.1,
NP_033892.2
|
| Others |
UniRef100:
UniRef100_P97443,
UniRef100_Q3UQT9
UniRef90:
UniRef90_P97443
UniRef50:
UniRef50_Q8NB12
UniGene:
Mm.234274,
Mm.440892
CCDS:
CCDS20227.2,
CCDS51805.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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