| Type | Description |
|---|---|
| Definition | bone morphogenetic protein 15 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 12:44:00 | GDF9 + BMP15, but not separately, significantly induce AMH expression in vitro and in vivo. GDF9 + BMP15, through the PI3K/Akt and Smad2/3 pathways synergistically recruit the coactivator p300 on the AMH promoter region that promotes acetylation of H3K27ac, facilitating AMH expression. | 30060157 |
| 2017-04-08 11:39:00 | these data provide evidence that the preovulatory LH surge leads to upregulation of several forms of BMP15 protein secreted by the oocyte for putative sequestration and/or interaction with ovarian follicular somatic cells. | 24548471 |
| 2017-03-04 11:12:00 | Data show that Rac1 induced nuclear import of by physical binding, and nuclear duanyu18133 directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 and BMP15. | 27050391 |
| 2015-12-19 10:10:00 | results support a model of activation for human GDF9 dependent on cumulin formation through heterodimerization with BMP15. Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals. | 26254468 |
| 2015-04-04 11:28:00 | modified oocyte glycoproteins alter GDF9:BMP15 expression modifying follicle development resulting in the generation of more follicles | 25416550 |
| Type | IDs |
|---|---|
| Synonymous | AU015375, AU018861, AU021453, Bmp-15, C86824, C87336, GDF-9B |
| Gene |
UniProtKB-ID:
BMP15_MOUSE
UniprotKB:
Q9Z0L4
UniParc:
UPI0000003F7D
EMBL:
AJ132406,
BC055363,
AF082348,
AJ010259,
AK028735,
AK135757,
AK139773
Ensembl:
ENSMUSG00000023279
KO:
mmu:12155
|
| Nucleutide sequences |
EMBL-CDS:
CAB40966.1,
BAE24134.1,
BAE22642.1,
BAC26090.1,
AAH55363.1,
AAC99766.1,
CAA09053.1
Ensembl_TRS:
ENSMUST00000024049
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024049
RefSeq:
NP_033887.1
|
| Others |
UniRef100:
UniRef100_Q9Z0L4
UniRef90:
UniRef90_Q9Z0L4
UniRef50:
UniRef50_O95972
UniGene:
Mm.42160
CCDS:
CCDS29958.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员