| Type | Description |
|---|---|
| Definition | FYVE, RhoGEF and PH domain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:58:00 | Circular RNA circFGD4 suppresses gastric cancer progression via modulating miR-532-3p/APC/beta-catenin signalling pathway. | 32633323 |
| 2020-10-10 12:57:00 | Identification of novel pathogenic copy number variations in Charcot-Marie-Tooth disease. | 31852984 |
| 2019-03-30 11:49:00 | Results show that the expression of FGD4 is upregulated in cancerous prostates compared to the luminal cells in benign prostatic hyperplasia and demonstrate a tumor promoting and a cell migratory function of FGD4 in prostate cancer cells. Its inhibition enhances the response for both androgen-dependent and independent prostate cancer cells towards currently used prostate cancer drugs. | 30558664 |
| 2017-05-27 11:55:00 | FGD4 c.2044-236 A-allele carriers had an increased risk of paclitaxel dose reduction (HR per A-allele=1.38, P=0.036) when adjusted for total cumulative paclitaxel dose | 27736846 |
| 2016-01-30 12:13:00 | identified two different pairs of novel compound heterozygous mutations in the FGD4 gene from nonconsanguineous Korean Charcot-Marie-Tooth disease type 4H families | 26400421 |
| Type | IDs |
|---|---|
| Synonymous | CMT4H, FRABP, ZFYVE6 |
| Gene |
UniProtKB-ID:
FGD4_HUMAN,
F8W1R0_HUMAN,
E9PJX4_HUMAN,
B7Z493_HUMAN,
B7Z8F9_HUMAN,
Q49A55_HUMAN
UniprotKB:
Q96M96,
F8W1R0,
E9PJX4,
B7Z493,
B7Z8F9,
Q49A55
UniParc:
UPI0001915010,
UPI00019152FD,
UPI00020CE036,
UPI0000037D64,
UPI000004CCA6,
UPI000056F1E0,
UPI0001F78470,
UPI00004E1942
EMBL:
AK057294,
AC087245,
BC045552,
AY367054,
AL713762,
AK303334,
AK297025,
AC084824,
AC090677,
AC090440
Ensembl:
ENSG00000139132
KO:
hsa:121512
|
| Nucleutide sequences |
EMBL-CDS:
CAD28532.1,
BAB71413.1,
AAQ72372.1,
BAH12479.1,
BAH13945.1,
AAH45552.1
Ensembl_TRS:
ENST00000427716,
ENST00000546442,
ENST00000525053,
ENST00000531134
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394487,
ENSP00000446695,
ENSP00000433666,
ENSP00000431323
RefSeq:
NP_001291410.1,
NP_001317302.1,
NP_001371057.1,
XP_011518861.1,
XP_024304607.1,
NP_001371060.1,
XP_024304608.1,
XP_024304605.1,
XP_011518856.1,
NP_001372047.1,
XP_011518860.1,
NP_001291413.1,
NP_001371055.1,
NP_001291412.1,
XP_011518857.1,
NP_001357227.2,
XP_011518858.1,
NP_001371056.1,
XP_011518859.1,
NP_001371061.1,
NP_001371059.1,
NP_640334.2,
XP_024304606.1,
XP_005253367.1,
NP_001291409.1,
NP_001357226.1,
NP_001317303.1,
XP_005253366.1
|
| Others |
UniRef100:
UniRef100_B7Z8F9,
UniRef100_Q96M96,
UniRef100_E9PJX4,
UniRef100_Q49A55,
UniRef100_B7Z493
UniRef90:
UniRef90_E9PJX4,
UniRef90_Q49A55,
UniRef90_Q96M96
UniRef50:
UniRef50_A0A3Q2TZP0,
UniRef50_Q49A55,
UniRef50_Q96M96
UniGene:
Hs.117835
CCDS:
CCDS8727.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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