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121504 HIST4H4

121504

HIST4H4

histone cluster 4 H4

protein-coding

Homo sapiens

基因描述

Type Description
Definition histone cluster 4 H4

研究结论

Date Results Publications
2017-12-16 11:38:00 ata show that PP32 and SET/TAF-Ibeta proteins block HAT1-mediated H4 acetylation. 28977641
2017-08-05 10:32:00 Data suggest post-translational modifications of histones, trimethylation of lysine 36 in H3 (H3K36me3) and acetylation of lysine 16 in H4 (H4K16ac), have roles in DNA damage repair; H3K36me3 stimulates H4K16ac upon DNA double-strand break; SETD2, LEDGF, and KAT5 are required for these epigenetic changes. (SETD2 = SET domain containing 2; LEDGF = lens epithelium-derived growth factor; KAT5 = lysine acetyltransferase 5) 28546430
2017-07-08 10:07:00 Data suggest that O-GlcNAc transferase 1 (OGT1) specifically binds to, O-GlcNAcylates, and stabilizes nonspecific lethal protein3 (NSL3); stabilization of NSL3 by OGT1 up-regulates global acetylation levels of histone 4 at Lys-5, Lys-8, and Lys-16. 28450392
2016-10-22 10:24:00 Data show that Omomyc protein co-localized with proto-oncogene protein c-myc (c-Myc), protein arginine methyltransferase 5 (PRMT5) and histone H4 H4R3me2s-enriched chromatin domains. 26563484
2016-01-16 10:45:00 H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription 25788266

名称对应

Type IDs
Synonymous H4/p
Gene
UniProtKB-ID: H4_HUMAN, B2R4R0_HUMAN
UniprotKB: P62805, B2R4R0
UniParc: UPI000000003C
EMBL: AY128662, CR542189, BC120939, BC111093, AB000905, BC069654, AL353759, AK316561, X00038, BC066248, BC093969, BC130558, CR542172, BC066249, AB451459, BC093763, X60482, BC017361, X83548, BC069288, AY648850, M60749, AF525682, X67081, BC067495, AL049822, CR542169, AL031777, AY128664, M16707, AY128659, BC111434, X60484, AY128653, X60483, BC054014, AK311916, X60481, Z98744, X60486, AL591493, BC130560, AK312153, BC128105, BC069392, AY128656, AY128657, BC112193, AY128655, CR542180, AK312028, AY128654, BC148271, CH471087, AY128665, Z80787, BC067497, AL021807, AY128661, CH471094, BC093765, AL021917, CH471081, BC128104, AY128658, BC067496, CR542187, AY128663, BC143045, BC066250, BC069467, X60487
Ensembl: ENSG00000278637, ENSG00000273542, ENSG00000270882, ENSG00000276966, ENSG00000276180, ENSG00000158406, ENSG00000197238, ENSG00000270276, ENSG00000274618, ENSG00000197837, ENSG00000275126, ENSG00000197061, ENSG00000278705, ENSG00000277157
KO: hsa:8363, hsa:8294, hsa:8367, hsa:8362, hsa:554313, hsa:8366, hsa:8365, hsa:8364, hsa:8368, hsa:8359, hsa:8370, hsa:8361, hsa:8360, hsa:121504
Nucleutide sequences
EMBL-CDS: EAW55510.1, AAI11435.1, AAH93969.1, CAA43016.1, AAN01442.1, AAH66250.1, AAN01444.1, AAN01449.1, AAA52652.1, CAI12567.1, AAH66248.1, AAH17361.1, CAA43014.1, CAG46986.1, AAH69392.1, CAA43012.1, AAN01447.1, AAH66249.1, AAN01438.1, CAA43011.1, AAN01439.1, CAB02549.1, AAI30559.1, CAI12560.1, CAA43013.1, AAH93765.1, AAN01440.1, EAW55555.1, AAN01443.1, AAI28106.1, AAH67497.1, CAA24918.1, EAW96325.1, AAM83108.1, EAW55538.1, AAI12194.1, CAA43017.1, BAA19208.1, AAT68253.1, CAA47464.1, AAA63188.1, AAN01448.1, AAH67496.1, AAI30561.1, CAG46969.1, AAH67495.1, CAA58538.1, AAN01446.1, EAW55549.1, CAG46977.1, EAX03086.1, AAH69654.1, AAH93763.1, CAG46966.1, AAH54014.1, AAI11094.1, EAX03121.1, AAN01450.1, AAH69288.1, EAX03112.1, CAG46984.1, AAN01441.1, AAI20940.1, EAW55509.1, AAH69467.1, EAX03111.1, AAI28105.1, AAI43046.1, BAG34857.1, AAI48272.1, BAG34965.1, EAW55556.1, BAG35087.1, BAG70273.1, BAG38150.1
Gene_ORFName: hCG_1640981
Ensembl_TRS: ENST00000614247, ENST00000615164, ENST00000579512, ENST00000634560, ENST00000244537, ENST00000612061, ENST00000621520, ENST00000634956, ENST00000614272, ENST00000377727, ENST00000578186, ENST00000613412, ENST00000355057, ENST00000617569, ENST00000377745, ENST00000618305, ENST00000611927, ENST00000635491, ENST00000618193, ENST00000377803, ENST00000539745, ENST00000358064, ENST00000615353
Protein sequencees
Ensembl_PRO: ENSP00000462667, ENSP00000367034, ENSP00000484789, ENSP00000479461, ENSP00000350767, ENSP00000462355, ENSP00000481486, ENSP00000478786, ENSP00000479106, ENSP00000481507, ENSP00000489567, ENSP00000489236, ENSP00000366974, ENSP00000244537, ENSP00000478519, ENSP00000443017, ENSP00000479794, ENSP00000481343, ENSP00000489319, ENSP00000347168, ENSP00000366956, ENSP00000482412, ENSP00000480960
RefSeq: NP_778224.1
Others
UniRef100: UniRef100_P62805
UniRef90: UniRef90_P62805
UniRef50: UniRef50_P62805
UniGene: Hs.745457
CCDS: CCDS4571.1, CCDS4593.1, CCDS4637.1, CCDS30851.1, CCDS4572.1, CCDS4620.1, CCDS8665.1, CCDS4604.1, CCDS4631.1, CCDS30847.1, CCDS4583.1, CCDS4630.1, CCDS4589.1, CCDS4598.1

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研究热度

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