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121441 NEDD1

121441

NEDD1

neural precursor cell expressed, developmentally down-regulated 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition neural precursor cell expressed, developmentally down-regulated 1

研究结论

Date Results Publications
2020-07-25 10:09:00 Authors show here that the expression of a NEDD1 isoform mimicking phosphorylation by Aurora A is sufficient to restore microtubule nucleation in the midzone under conditions of Aurora A inhibition. 31028180
2013-08-10 12:21:00 One important function of Aurora A in mitotic cells is to promote microtubule nucleation around the chromatin by phosphorylating NEDD1, and thereby to promote functional spindle assembly. 23273898
2013-07-06 12:33:00 The mice treated with small interfering (si) RNA targeting NEDD1 by the atelocollagen-mediated delivery system showed a significantly prolonged survival in a xenograft model of human gastric cancer. 23106787
2013-05-18 10:27:00 Data suggest that the NEDD1/gamma-tubulin interaction is finely tuned by multiple phosphorylation events in the S557-S574 region and is critical for spindle assembly. 22595525
2013-01-12 10:02:00 Nek9 phosphorylates NEDD1 on Ser377 driving its recruitment and thereby that of gamma-tubulin to the centrosome in mitotic cells. 22818914

名称对应

Type IDs
Synonymous GCP-WD, TUBGCP7
Gene
UniProtKB-ID: NEDD1_HUMAN, A0A024RBE5_HUMAN, A8K1Z3_HUMAN
UniprotKB: Q8NHV4, A0A024RBE5, A8K1Z3
UniParc: UPI00001FB32B, UPI000004D249, UPI00015DA593, UPI000004F17B
EMBL: AK303656, AC007564, AC013417, AK290058, BC027605, CH471054, AK093221, AK315821
Ensembl: ENSG00000139350
KO: hsa:121441
Nucleutide sequences
EMBL-CDS: BAC04099.1, EAW97577.1, BAF98712.1, BAG64657.1, AAH27605.1, EAW97579.1, EAW97580.1, EAW97578.1, BAF82747.1
Gene_ORFName: hCG_33123
Ensembl_TRS: ENST00000411739, ENST00000557644, ENST00000457368, ENST00000266742, ENST00000429527
Protein sequencees
Ensembl_PRO: ENSP00000266742, ENSP00000404978, ENSP00000407964, ENSP00000411307, ENSP00000451211
RefSeq: NP_001128649.1, NP_001128648.1, XP_011536207.1, XP_016874290.1, XP_011536206.1, XP_011536205.1, XP_011536208.1, NP_690869.1, XP_024304603.1, XP_006719300.1, XP_016874291.1, XP_005268701.1, NP_001128647.1
Others
UniRef100: UniRef100_A8K1Z3, UniRef100_Q8NHV4
UniRef90: UniRef90_Q8NHV4
UniRef50: UniRef50_Q8NHV4
UniGene: Hs.270084
CCDS: CCDS44956.1, CCDS9063.1, CCDS44955.1

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