| Type | Description |
|---|---|
| Definition | keratin 74 |
| Date | Results | Publications |
|---|---|---|
| 2014-11-29 12:27:00 | These observations show for the first time that homozygosity for a KRT74 missense variant may be associated with autosomal recessive pure hair and nail ectodermal dysplasia. | 24714551 |
| 2011-06-18 10:10:00 | Data provide evidence implicating that the KRT74 gene in the pathogenesis of autosomal dominant hair loss disorders. | 21188418 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-05-03 12:09:00 | in KRT74 gene is associated with woolly hair. | 20346438 |
| 2010-01-21 00:00:00 | report on the cloning of two novel human type II keratin cDNAs, K6irs3 and K6irs4, which were specifically expressed in the inner root sheath of the hair follicle | 12648212 |
| Type | IDs |
|---|---|
| Synonymous | ADWH, HTSS2, HYPT3, K6IRS4, KRT5C, KRT6IRS4 |
| Gene |
UniProtKB-ID:
K2C74_HUMAN
UniprotKB:
Q7RTS7
UniParc:
UPI00001AEDF9
EMBL:
CH471054,
AC055715,
BK000977,
AJ508777
Ensembl:
ENSG00000170484
KO:
hsa:121391
|
| Nucleutide sequences |
EMBL-CDS:
DAA00404.1,
CAD48514.1,
EAW96637.1
Ensembl_TRS:
ENST00000305620
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307240
RefSeq:
NP_778223.2
|
| Others |
UniRef100:
UniRef100_Q7RTS7
UniRef90:
UniRef90_Q7RTS7
UniRef50:
UniRef50_P19013
UniGene:
Hs.660125
CCDS:
CCDS8832.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员