| Type | Description |
|---|---|
| Definition | solute carrier family 15 member 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:58:00 | identification of TASL as the component that links endolysosomal TLRs to the IRF5 transcription factor via SLC15A4 provides a mechanistic explanation for the involvement of these proteins in systemic lupus erythematosus | 32433612 |
| 2019-12-28 11:33:00 | The transporters PEPT2, PHT1, and PHT2 are responsible for the uptake of carnosine into glioblastoma cells and full function of all three transporters is required for maximum uptake. | 31073693 |
| 2019-03-09 10:07:00 | Study established a novel cell model to evaluate the function of hPHT1 in vitro and confirmed that muramyl peptide and Tri-DAP were substrates of hPHT1. | 29224352 |
| 2018-12-22 10:11:00 | Targeted sequencing of two candidate genes, SLC20A1 and SLC15A4, of the solute carrier membrane transport protein family in 200 additional patients demonstrated two further variants predicted as damaging for combined hormone deficiency. | 29261175 |
| 2017-04-08 10:45:00 | Under a dominant model the rs1385374 (TT+CT) SNP carried a higher risk of Systemic Lupus Erythematosus (SLE) than (CC). Under a codominant model the genotype frequencies of rs3765108 AG and rs7308691 AT were significantly higher in the SLE group than the control group. One SLC15A4 haplotype (TA), which consists of 2 SNPs (rs959989 and rs983492), was associated with SLE | 27362648 |
| Type | IDs |
|---|---|
| Synonymous | FP12591, PHT1, PTR4 |
| Gene |
UniProtKB-ID:
S15A4_HUMAN
UniprotKB:
Q8N697
UniParc:
UPI000006F120,
UPI00003E5EDF
EMBL:
AK095717,
AF461893,
AY038999,
BC146803,
BC028394,
AY050629,
CH471054
Ensembl:
ENSG00000139370
KO:
hsa:121260
|
| Nucleutide sequences |
EMBL-CDS:
BAG53113.1,
EAW98494.1,
AAI46804.1,
AAQ04807.1,
AAH28394.2,
AAK72099.1,
AAK95565.1
Gene_ORFName:
FP12591
Ensembl_TRS:
ENST00000266771
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000266771
RefSeq:
XP_016874282.1,
XP_016874280.1,
XP_011536197.1,
NP_663623.1,
XP_016874281.1
|
| Others |
UniRef100:
UniRef100_Q8N697
UniRef90:
UniRef90_Q8N697
UniRef50:
UniRef50_Q8N697
UniGene:
Hs.507260
CCDS:
CCDS9264.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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