| Type | Description |
|---|---|
| Definition | harakiri, BCL2 interacting protein (contains only BH3 domain) |
| Date | Results | Publications |
|---|---|---|
| 2011-12-24 10:27:00 | Hrk deficiency does not significantly attenuate the widespread apoptosis seen in the Bcl-x (-/-) embryonic nervous system, indicating that other BH3-only molecules, alone or in combination, may regulate BAX activation in immature neurons. | 22043021 |
| 2010-01-21 00:00:00 | These results demonstrate that HRK contributes to apoptosis signalling elicited by trophic factor withdrawal in certain neuronal populations but is dispensable for apoptosis of haematopoietic cells. | 17535852 |
| 2010-01-21 00:00:00 | DP5 plays an important role in neuronal cell death induced by axotomy and NGF deprivation through the regulation of mitochondrial function and caspase-3 activation | 15084651 |
| 2010-01-21 00:00:00 | The effect of antisense oligonucleoties specific to the harakiri mRNA on spontaneous and induced defects of mouse preimplantation embryo development | 18846829 |
| 2010-01-21 00:00:00 | in response to PAHs, Ahr-mediated activation of the harakiri, BCL2 interacting protein (contains only BH3 domain), was necessary for execution of cell death. | 18037991 |
| Type | IDs |
|---|---|
| Synonymous | AI838259, Bid3, DP5, harakiri |
| Gene |
UniProtKB-ID:
HRK_MOUSE
UniprotKB:
P62816
UniParc:
UPI0000026EF9
EMBL:
D83698
Ensembl:
ENSMUSG00000046607
KO:
mmu:12123
|
| Nucleutide sequences |
EMBL-CDS:
BAA12066.1
Ensembl_TRS:
ENSMUST00000054836
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000057532
RefSeq:
NP_031571.1
|
| Others |
UniRef100:
UniRef100_P62816
UniRef90:
UniRef90_P62816
UniRef50:
UniRef50_O00198
UniGene:
Mm.384468
CCDS:
CCDS39236.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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