| Type | Description |
|---|---|
| Definition | BH3 interacting domain death agonist |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 11:42:00 | Bid monomers lie shallowly on the lipid bilayer, where they self-assemble to form oligomers. During the initiation phase of self-assembly, the two central hydrophobic helices (alpha6 and alpha7) of Bid insert halfway into the phospholipid core, while the other helices remain on the surface. | 31558028 |
| 2019-04-20 11:02:00 | Bid promotes E3 ubiquitin ligase-mediated signaling downstream of TLR3 and TLR4 inducing a pro-inflammatory response. | 29720226 |
| 2019-03-02 10:53:00 | These results identify a role for Bid in homeostatic mitochondrial cristae reorganization, that we link to human cardiac disease. | 30281024 |
| 2018-09-01 10:40:00 | we show that BID is an important regulator downstream of FAS in mouse neutrophils. Loss of BID significantly delays FASL-cell death and partially counteracts the switch from apoptosis to necroptosis when caspases are blocked. | 29495595 |
| 2018-03-24 10:54:00 | Study exposes BID as the molecular link between the previously separated pathways of oxidative stress signaling by merging the death pathways of ferroptosis and oxytosis at the level of mitochondria, i.e. the crucial point of decision for neuronal function and survival. | 28384611 |
| Type | IDs |
|---|---|
| Synonymous | 2700049M22Rik, AI875481, AU022477 |
| Gene |
UniProtKB-ID:
BID_MOUSE
UniprotKB:
P70444
UniParc:
UPI00000E886A
EMBL:
U75506,
AK051076,
AK077657,
AK045731,
AK052356,
AK161235,
BC002031
Ensembl:
ENSMUSG00000004446
KO:
mmu:12122
|
| Nucleutide sequences |
EMBL-CDS:
BAC34518.1,
BAC36932.1,
BAE36258.1,
AAC71064.1,
BAC34955.1,
BAC32475.1,
AAH02031.1
Ensembl_TRS:
ENSMUST00000160684,
ENSMUST00000004560
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125731,
ENSMUSP00000004560
RefSeq:
XP_006505474.1,
XP_006505472.1,
XP_036021660.1,
NP_031570.2,
XP_006505473.1
|
| Others |
UniRef100:
UniRef100_P70444
UniRef90:
UniRef90_P70444
UniRef50:
UniRef50_P70444
UniGene:
Mm.235081
CCDS:
CCDS20486.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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