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12116 Bhmt

12116

Bhmt

betaine-homocysteine methyltransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition betaine-homocysteine methyltransferase

研究结论

Date Results Publications
2020-07-18 11:31:00 This study uncovered a novel antisense lncRNA (Bhmt-AS) that is co-expressed with Bhmt and concordantly and specifically regulates Bhmt expression both in vitro and in vivo to regulate hepatic gluconeogenesis. 31208716
2020-06-06 12:08:00 BHMT plays a central role in the homeostasis of cochlear methionine metabolism and Bhmt2 up-regulation could carry out a compensatory role in cochlear protection against noise injury in the absence of BHMT 30753104
2020-05-16 11:33:00 Taurine treatment induced BHMT expression in HCU mice by 5-fold and restored maximal lowering of Hcy levels during long-term betaine treatment with a concomitant normalization of inflammatory cytokine expression and a significantly improved coagulative phenotype. 30768359
2018-10-27 10:39:00 Data indicate that improved Sp1 transcription factor (Sp1) and betaine homocysteine-S-methyltransferase (BHMT) expression are involved in the effects of zinc on oxidative stress. 29204947
2018-07-07 11:20:00 Bhmt(-/-) mice maintained on a control diet had elevated concentrations of homocysteine, reduced total brain magnetic resonance imaging volume, as well as impaired reference and short-term memories. 28715642

名称对应

Type IDs
Gene
UniProtKB-ID: BHMT1_MOUSE
UniprotKB: O35490
UniParc: UPI0000000895
EMBL: AK145668, AK149457, AK166818, BC110307, BC037004, AF033381, AH009623, BC093510, AK166754
Ensembl: ENSMUSG00000074768, ENSMUSG00000069324
KO: mmu:12116
Nucleutide sequences
EMBL-CDS: BAE26578.1, AAH37004.1, BAE38995.1, AAB87501.1, AAH93510.1, BAE39044.1, BAE28890.1, AAF85944.1, AAI10308.1
Ensembl_TRS: ENSMUST00000099309, ENSMUST00000091776
Protein sequencees
Ensembl_PRO: ENSMUSP00000096912, ENSMUSP00000135956
RefSeq: NP_057877.1
Others
UniRef100: UniRef100_O35490
UniRef90: UniRef90_O35490
UniRef50: UniRef50_O35490
UniGene: Mm.329582, Mm.423099
CCDS: CCDS36748.1

全选

研究热度

研究结论
热点单位
排名 科研单位 文献
1

University of North Carolina

3
2

RIKEN Yokohama Institute

2
3

National Cancer Institute

2
4

Broad Institute MIT and Harvard

1
5

Institute of Cell Biology and Neurobiology

1
热点人员
排名 研究人员 文献
1

P Carninci

7
2

Y Hayashizaki

6
3

Steven H Zeisel

6
4

H Konno

5
5

K Shibata

5
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