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12057 Opn1sw

12057

Opn1sw

opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)

protein-coding

Mus musculus

基因描述

Type Description
Definition opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)

研究结论

Date Results Publications
2021-03-20 13:30:00 True S-cones are concentrated in the ventral mouse retina and wired for color detection in the upper visual field. 32463363
2018-02-10 11:53:00 These findings indicate that the aggregation of S-opsin induced by exposure to blue -emitting diode light causes endoplasmic reticulum stress, and ATF4 activation in particular. 28331281
2017-07-15 12:00:00 quantitative FRET analysis in acutely isolated cone OS revealed that the cone degeneration-causing V268I mutation in peripherin-2 selectively reduced binding to M-opsin without affecting the peripherin-2 interaction to S-opsin or rhodopsin 27033727
2015-11-28 10:47:00 Deletion of one allele of S-opsin from Lrat(-) (/-) mice (model of Leber congenital amaurosis) is sufficient to prevent rapid cone degeneration for at least 1 month. Deletion of both alleles of S-opsin prevents cone degeneration for at least 12 months. 25416279
2010-01-21 00:00:00 Thus, the three types of mouse opsin appear distinctive in the degree to which their bleached, unregenerated opsins generate "dark light." 16567464

名称对应

Type IDs
Synonymous AW551857, Bcp
Gene
UniProtKB-ID: OPSB_MOUSE
UniprotKB: P51491
UniParc: UPI000000091C
EMBL: U92559, AF190671, BC058267, U92560, BC026021, U49720, U92562, U92561, AF190670, U92558
Ensembl: ENSMUSG00000058831
KO: mmu:12057
Nucleutide sequences
EMBL-CDS: AAB53320.1, AAG17989.1, AAH58267.1, AAG17990.1, AAH26021.1, AAA92458.1
Ensembl_TRS: ENSMUST00000080428
Protein sequencees
Ensembl_PRO: ENSMUSP00000079289
RefSeq: NP_031564.1
Others
UniRef100: UniRef100_P51491
UniRef90: UniRef90_P51491
UniRef50: UniRef50_P51491
UniGene: Mm.56987
CCDS: CCDS19959.1

全选

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