| Type | Description |
|---|---|
| Definition | BCL2-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | BCL-XL exerts a protective role against anemia caused by radiation-induced kidney damage. | 33236795 |
| 2020-10-10 13:01:00 | Let-7a inhibits Bcl-xl and YAP1 expression to induce apoptosis of trophoblast cells in early-onset severe preeclampsia. | 32721616 |
| 2020-10-03 12:50:00 | Mcl-1 and Bcl-xL are essential for survival of the developing nervous system. | 30361616 |
| 2019-10-12 11:44:00 | Data indicate a role for ROR-gamma (RORgammat) and Bcl-XL protein (Bcl-xL) in limiting interleukin 2 receptor gamma chain (gammac) abundance at the cell surface. | 30154103 |
| 2019-09-14 12:52:00 | Bcl-xL could sequester Bak in response to the BH3 mimetic ABT-737, despite this molecule targeting Bcl-xL. These findings highlight the importance of Bak sequestration in resistance to anti-cancer treatments, including BH3 mimetics. | 29459767 |
| Type | IDs |
|---|---|
| Synonymous | Bcl(X)L, Bcl-XL, Bcl2l, BclX, bcl-x, bcl2-L-1 |
| Gene |
UniProtKB-ID:
B2CL1_MOUSE,
O35843_MOUSE,
Q5HZH3_MOUSE
UniprotKB:
Q64373,
O35843,
Q5HZH3
UniParc:
UPI000002A4C6,
UPI000002A4C7,
UPI0000022BE9,
UPI000002A4C8,
UPI000002103C
EMBL:
L35048,
BC089016,
U10101,
AY902314,
U10100,
U51277,
U78030,
U78031,
X83574,
L35049,
U51278,
AK146461,
BC089017,
U10102,
U51279
Ensembl:
ENSMUSG00000007659
KO:
mmu:12048
|
| Nucleutide sequences |
EMBL-CDS:
AAA82172.1,
AAC53460.1,
AAA51039.1,
AAB96881.1,
AAA51040.1,
AAA82173.1,
CAA58557.1,
AAC53459.1,
AAA82174.1,
AAC53458.1,
BAE27189.1,
AAH89016.1,
AAH89017.1,
AAX90599.1
Ensembl_TRS:
ENSMUST00000140436,
ENSMUST00000007803,
ENSMUST00000134902,
ENSMUST00000109820
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000134596,
ENSMUSP00000105445,
ENSMUSP00000134614,
ENSMUSP00000007803
RefSeq:
NP_033873.3,
XP_011237562.1,
NP_001341982.1,
XP_006498675.1,
NP_001276668.1,
NP_001276645.1,
XP_006498674.1,
NP_001276646.1
|
| Others |
UniRef100:
UniRef100_Q64373,
UniRef100_O35843
UniRef90:
UniRef90_O35843,
UniRef90_Q64373
UniRef50:
UniRef50_Q07817-3,
UniRef50_P53563
UniGene:
Mm.238213
CCDS:
CCDS16899.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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