| Type | Description |
|---|---|
| Definition | B cell leukemia/lymphoma 2 related protein A1a |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | The pro-survival Bcl-2 family member A1 delays spontaneous and FAS ligand-induced apoptosis of activated neutrophils. | 32555150 |
| 2019-03-30 10:21:00 | MicroRNA-326 aggravates acute lung injury in septic shock by mediating the NF-kappaB signaling pathway via BCL2A1. | 29727715 |
| 2018-02-17 11:06:00 | The findings support a model in which survival is determined by quantitative participation of multiple anti-apoptotic proteins, BCL2, Mcl1, and BCL2A1, rather than by a single anti-apoptotic protein. | 28362427 |
| 2018-02-10 10:46:00 | This dynamic change in B cell survival mechanisms is unique to Epstein-Barr virus-infected cells and relies on regulation of MCL-1 mitochondrial localization and BFL-1 transcription by the viral EBNA3A protein. | 28425914 |
| 2018-01-20 10:52:00 | Loss of A1 alone does not impair T cell-driven immune responses. It therefore appears likely that A1 has critical overlapping functions with other pro-survival BCL-2 proteins in T cell immune responses. | 28085151 |
| Type | IDs |
|---|---|
| Synonymous | A1, BB218357, Bcl2a1, Bfl-1, Hbpa1 |
| Gene |
UniProtKB-ID:
B2LA1_MOUSE
UniprotKB:
Q07440
UniParc:
UPI0000027C48
EMBL:
U23773,
L16462,
U23774
Ensembl:
ENSMUSG00000102037
KO:
mmu:12044
|
| Nucleutide sequences |
EMBL-CDS:
AAA16886.1,
AAB97953.1
Ensembl_TRS:
ENSMUST00000098485
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096086
RefSeq:
NP_033872.1
|
| Others |
UniRef100:
UniRef100_Q07440
UniRef90:
UniRef90_Q07440
UniRef50:
UniRef50_Q07440
UniGene:
Mm.425593,
Mm.479217
CCDS:
CCDS23391.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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