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12041 Bckdk

12041

Bckdk

branched chain ketoacid dehydrogenase kinase

protein-coding

Mus musculus

基因描述

Type Description
Definition branched chain ketoacid dehydrogenase kinase

研究结论

Date Results Publications
2014-10-04 12:51:00 leucine supplementation increased the expression of enzymes (BCAT1, BCAT2 and BCKDK) that metabolize branched-chain amino acids. 24349566
2013-08-31 12:33:00 Results suggest that targeting mitochondrial BCKD kinase (BDK) as a pharmacological approach to mitigate the branched-chain amino acids (BCAAs) accumulation in metabolic diseases and heart failure. 23716694
2010-01-21 00:00:00 branched-chain a-keto acid dehydrogenase complex kinase plays an important role in conserving branched-chain amino acids by limiting their oxidation 16875466
2010-01-21 00:00:00 Tissue-specific translation of murine BCKDK mRNA is dependent upon an upstream open reading frame in the 5'-untranslated region 15302860

名称对应

Type IDs
Synonymous AI327402
Gene
UniProtKB-ID: BCKD_MOUSE, Q3UCB5_MOUSE
UniprotKB: O55028, Q3UCB5
UniParc: UPI000000BA3D
EMBL: AK145479, AK167519, AK150607, BC046595, AF043070
Ensembl: ENSMUSG00000030802
KO: mmu:12041
Nucleutide sequences
EMBL-CDS: AAB97689.1, AAH46595.1, BAE26459.1, BAE39591.1, BAE29698.1
Ensembl_TRS: ENSMUST00000071056
Protein sequencees
Ensembl_PRO: ENSMUSP00000070345
RefSeq: NP_033869.1
Others
UniRef100: UniRef100_O55028
UniRef90: UniRef90_O55028
UniRef50: UniRef50_O55028
UniGene: Mm.425495
CCDS: CCDS21884.1

全选

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研究热度

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