| Type | Description |
|---|---|
| Definition | transmembrane protein 45B |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 11:04:00 | increased expression of TMEM45B appears to be significantly associated with prostate carcinoma progression and metastasis | 30249106 |
| 2018-10-06 10:14:00 | TMEM45B may be a new potent therapeutic molecule for the treatment of gastric cancer. | 29803169 |
| 2018-03-31 12:06:00 | TMEM45B plays an important role in regulating the proliferation, migration, and invasion of osteosarcoma cells. | 28244852 |
| 2017-07-29 11:02:00 | TMEM45B expression was significantly upregulated in pancreatic cancer tissues and cell lines. Moreover, TMEM45B was significantly positively correlated with the cell cycle and metastasis up pathways and regulated expression of proteins involved. This indicates an important role of TMEM45B in pancreatic cancer carcinogenesis. | 27108650 |
| 2017-02-25 12:22:00 | Data show that transmembrane protein 45B (TMEM45B) was overexpressed in lung cancer and its expression correlated with overall survival of patients. | 27225290 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TM45B_HUMAN
UniprotKB:
Q96B21
UniParc:
UPI0000039E75
EMBL:
AK292058,
BC016153,
AK098106,
AK290283
Ensembl:
ENSG00000151715
KO:
hsa:120224
|
| Nucleutide sequences |
EMBL-CDS:
BAF82972.1,
BAF84747.1,
AAH16153.1,
BAC05235.1
Ensembl_TRS:
ENST00000281441,
ENST00000524567
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000436293,
ENSP00000281441
RefSeq:
NP_001318141.1,
NP_001318140.1,
XP_016872677.1,
XP_016872678.1,
NP_620143.1,
NP_001318139.1
|
| Others |
UniRef100:
UniRef100_Q96B21
UniRef90:
UniRef90_Q96B21
UniRef50:
UniRef50_Q96B21
UniGene:
Hs.504301
CCDS:
CCDS8482.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30249106 |
TMEM45B is a novel predictive biomarker for prostate cancer progression and metastasis. Neoplasma F Luo , K Yang , Y Z Wang , D Lin |
2018-09-19 | - |
| 29803169 |
Knockdown of TMEM45B inhibits cell proliferation and invasion in gastric cancer. Biomed. Pharmacother. Kexin Shen , Wei Yu , Yanhui Yu , Xiumin Liu , Xiaofeng Cui |
2018-08-01 | - |
| 28244852 |
Oncol Res Yan Li , Wei Guo , Shen Liu , Bin Zhang , Bing-Bing Yu , Bo Yang , Shun-Li Kan , Shi-Qing Feng |
2017-07-05 | - |
| 27225290 |
TMEM45B, up-regulated in human lung cancer, enhances tumorigenicity of lung cancer cells. Tumour Biol. Rui Hu , Fengqing Hu , Xiao Xie , Lei Wang , Guoqing Li , Tong Qiao , Mingsong Wang , Haibo Xiao |
2016-05-26 | - |
| 27108650 |
Mol Biosyst Liang-Chao Zhao , Bai-Yong Shen , Xia-Xing Deng , Hao Chen , Zheng-Gang Zhu , Cheng-Hong Peng |
2016-05-24 | - |
| 22238593 |
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS ONE Nicholette D Palmer , Caitrin W McDonough , Pamela J Hicks , Bong H Roh , Maria R Wing , S Sandy An , Jessica M Hester , Jessica N Cooke , Meredith A Bostrom , Megan E Rudock , Matthew E Talbert , Joshua P Lewis , DIAGRAM Consortium , MAGIC Investigators , Assiamira Ferrara , Lingyi Lu , Julie T Ziegler , Michele M Sale , Jasmin Divers , Daniel Shriner , Adebowale Adeyemo , Charles N Rotimi , Maggie C Y Ng , Carl D Langefeld , Barry I Freedman , Donald W Bowden , Benjamin F Voight , Laura J Scott , Valgerdur Steinthorsdottir , Andrew P Morris , Christian Dina , Ryan P Welch , Eleftheria Zeggini , Cornelia Huth , Yurii S Aulchenko , Gudmar Thorleifsson , Laura J McCulloch , Teresa Ferreira , Harald Grallert , Najaf Amin , Guanming Wu , Cristen J Willer , Soumya Raychaudhuri , Steve A McCarroll , Claudia Langenberg , Oliver M Hofmann , Josée Dupuis , Lu Qi , Ayellet V Segrè , Mandy van Hoek , Pau Navarro , Kristin Ardlie , Beverley Balkau , Rafn Benediktsson , Amanda J Bennett , Roza Blagieva , Eric Boerwinkle , Lori L Bonnycastle , Kristina Bengtsson Boström , Bert Bravenboer , Suzannah Bumpstead , Noël P Burtt , Guillaume Charpentier , Peter S Chines , Marilyn Cornelis , David J Couper , Gabe Crawford , Alex S F Doney , Katherine S Elliott , Amanda L Elliott , Michael R Erdos , Caroline S Fox , Christopher S Franklin , Martha Ganser , Christian Gieger , Niels Grarup , Todd Green , Simon Griffin , Christopher J Groves , Candace Guiducci , Samy Hadjadj , Neelam Hassanali , Christian Herder , Bo Isomaa , Anne U Jackson , Paul R V Johnson , Torben Jørgensen , Wen H L Kao , Norman Klopp , Augustine Kong , Peter Kraft , Johanna Kuusisto , Torsten Lauritzen , Man Li , Aloysius Lieverse , Cecilia M Lindgren , Valeriya Lyssenko , Michel Marre , Thomas Meitinger , Kristian Midthjell , Mario A Morken , Narisu Narisu , Peter Nilsson , Katharine R Owen , Felicity Payne , John R B Perry , Ann-Kristin Petersen , Carl Platou , Christine Proença , Inga Prokopenko , Wolfgang Rathmann , N William Rayner , Neil R Robertson , Ghislain Rocheleau , Michael Roden , Michael J Sampson , Richa Saxena , Beverley M Shields , Peter Shrader , Gunnar Sigurdsson , Thomas Sparsø , Klaus Strassburger , Heather M Stringham , Qi Sun , Amy J Swift , Barbara Thorand , Jean Tichet , Tiinamaija Tuomi , Rob M van Dam , Timon W van Haeften , Thijs van Herpt , Jana V van Vliet-Ostaptchouk , G Bragi Walters , Michael N Weedon , Cisca Wijmenga , Jacqueline Witteman , Richard N Bergman , Stephane Cauchi , Francis S Collins , Anna L Gloyn , Ulf Gyllensten , Torben Hansen , Winston A Hide , Graham A Hitman , Albert Hofman , David J Hunter , Kristian Hveem , Markku Laakso , Karen L Mohlke , Andrew D Morris , Colin N A Palmer , Peter P Pramstaller , Igor Rudan , Eric Sijbrands , Lincoln D Stein , Jaakko Tuomilehto , Andre Uitterlinden , Mark Walker , Nicholas J Wareham , Richard M Watanabe , Goncalo R Abecasis , Bernhard O Boehm , Harry Campbell , Mark J Daly , Andrew T Hattersley , Frank B Hu , James B Meigs , James S Pankow , Oluf Pedersen , H-Erich Wichmann , Inês Barroso , Jose C Florez , Timothy M Frayling , Leif Groop , Rob Sladek , Unnur Thorsteinsdottir , James F Wilson , Thomas Illig , Philippe Froguel , Cornelia M van Duijn , Kari Stefansson , David Altshuler , Michael Boehnke , Mark I McCarthy , Nicole Soranzo , Eleanor Wheeler , Nicole L Glazer , Nabila Bouatia-Naji , Reedik Mägi , Joshua Randall , Toby Johnson , Paul Elliott , Denis Rybin , Peter Henneman , Abbas Dehghan , Jouke Jan Hottenga , Kijoung Song , Anuj Goel , Josephine M Egan , Taina Lajunen , Alex Doney , Stavroula Kanoni , Christine Cavalcanti-Proença , Meena Kumari , Nicholas J Timpson , Carina Zabena , Erik Ingelsson , Ping An , Jeffrey O'Connell , Jian'an Luan , Amanda Elliott , Steven A McCarroll , Rosa Maria Roccasecca , François Pattou , Praveen Sethupathy , Yavuz Ariyurek , Philip Barter , John P Beilby , Yoav Ben-Shlomo , Sven Bergmann , Murielle Bochud , Amélie Bonnefond , Knut Borch-Johnsen , Yvonne Böttcher , Eric Brunner , Suzannah J Bumpstead , Yii-Der Ida Chen , Peter Chines , Robert Clarke , Lachlan J M Coin , Matthew N Cooper , Laura Crisponi , Ian N M Day , Eco J C de Geus , Jerome Delplanque , Annette C Fedson , Antje Fischer-Rosinsky , Nita G Forouhi , Rune Frants , Maria Grazia Franzosi , Pilar Galan , Mark O Goodarzi , Jürgen Graessler , Scott Grundy , Rhian Gwilliam , Göran Hallmans , Naomi Hammond , Xijing Han , Anna-Liisa Hartikainen , Caroline Hayward , Simon C Heath , Serge Hercberg , Andrew A Hicks , David R Hillman , Aroon D Hingorani , Jennie Hui , Joe Hung , Antti Jula , Marika Kaakinen , Jaakko Kaprio , Y Antero Kesaniemi , Mika Kivimaki , Beatrice Knight , Seppo Koskinen , Peter Kovacs , Kirsten Ohm Kyvik , G Mark Lathrop , Debbie A Lawlor , Olivier Le Bacquer , Cécile Lecoeur , Yun Li , Robert Mahley , Massimo Mangino , Alisa K Manning , MarÃa Teresa MartÃnez-Larrad , Jarred B McAteer , Ruth McPherson , Christa Meisinger , David Melzer , David Meyre , Braxton D Mitchell , Sutapa Mukherjee , Silvia Naitza , Matthew J Neville , Ben A Oostra , Marco Orrù , Ruth Pakyz , Giuseppe Paolisso , Cristian Pattaro , Daniel Pearson , John F Peden , Nancy L Pedersen , Markus Perola , Andreas F H Pfeiffer , Irene Pichler , Ozren Polasek , Danielle Posthuma , Simon C Potter , Anneli Pouta , Michael A Province , Bruce M Psaty , Nigel W Rayner , Kenneth Rice , Samuli Ripatti , Fernando Rivadeneira , Olov Rolandsson , Annelli Sandbaek , Manjinder Sandhu , Serena Sanna , Avan Aihie Sayer , Paul Scheet , Udo Seedorf , Stephen J Sharp , Beverley Shields , Eric J G Sijbrands , Angela Silveira , Laila Simpson , Andrew Singleton , Nicholas L Smith , Ulla Sovio , Amy Swift , Holly Syddall , Ann-Christine Syvänen , Toshiko Tanaka , Anke Tönjes , André G Uitterlinden , Ko Willems van Dijk , Dhiraj Varma , Sophie Visvikis-Siest , Veronique Vitart , Nicole Vogelzangs , Gérard Waeber , Peter J Wagner , Andrew Walley , Kim L Ward , Hugh Watkins , Sarah H Wild , Gonneke Willemsen , Jaqueline C M Witteman , John W G Yarnell , Diana Zelenika , Björn Zethelius , Guangju Zhai , Jing Hua Zhao , M Carola Zillikens , Ingrid B Borecki , Ruth J F Loos , Pierre Meneton , Patrik K E Magnusson , David M Nathan , Gordon H Williams , Kaisa Silander , Veikko Salomaa , George Davey Smith , Stefan R Bornstein , Peter Schwarz , Joachim Spranger , Fredrik Karpe , Alan R Shuldiner , Cyrus Cooper , George V Dedoussis , Manuel Serrano-RÃos , Lars Lind , Lyle J Palmer , Paul W Franks , Shah Ebrahim , Michael Marmot , W H Linda Kao , Peter Paul Pramstaller , Alan F Wright , Michael Stumvoll , Anders Hamsten , Thomas A Buchanan , Timo T Valle , Jerome I Rotter , David S Siscovick , Brenda W J H Penninx , Dorret I Boomsma , Panos Deloukas , Timothy D Spector , Luigi Ferrucci , Antonio Cao , Angelo Scuteri , David Schlessinger , Manuela Uda , Aimo Ruokonen , Marjo-Riitta Jarvelin , Dawn M Waterworth , Peter Vollenweider , Leena Peltonen , Vincent Mooser , Robert Sladek |
2012-01-01 | - |
| 22383897 |
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer. PLoS Genet Jirong Long , Qiuyin Cai , Hyuna Sung , Jiajun Shi , Ben Zhang , Ji-Yeob Choi , Wanqing Wen , Ryan J Delahanty , Wei Lu , Yu-Tang Gao , Hongbing Shen , Sue K Park , Kexin Chen , Chen-Yang Shen , Zefang Ren , Christopher A Haiman , Keitaro Matsuo , Mi Kyung Kim , Ui Soon Khoo , Motoki Iwasaki , Ying Zheng , Yong-Bing Xiang , Kai Gu , Nathaniel Rothman , Wenjing Wang , Zhibin Hu , Yao Liu , Keun-Young Yoo , Dong-Young Noh , Bok-Ghee Han , Min Hyuk Lee , Hong Zheng , Lina Zhang , Pei-Ei Wu , Ya-Lan Shieh , Sum Yin Chan , Shenming Wang , Xiaoming Xie , Sung-Won Kim , Brian E Henderson , Loic Le Marchand , Hidemi Ito , Yoshio Kasuga , Sei-Hyun Ahn , Han Sung Kang , Kelvin Y K Chan , Hiroji Iwata , Shoichiro Tsugane , Chun Li , Xiao-Ou Shu , Dae-Hee Kang , Wei Zheng |
2012-01-01 | - |
| 23251661 |
PLoS One Anthony G Comuzzie , Shelley A Cole , Sandra L Laston , V Saroja Voruganti , Karin Haack , Richard A Gibbs , Nancy F Butte |
2012-01-01 | - |
| 21988832 |
Toward an understanding of the protein interaction network of the human liver. Mol. Syst. Biol. Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang |
2011-10-11 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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