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12020 Nkx3-2

12020

Nkx3-2

NK3 homeobox 2

protein-coding

Mus musculus

基因描述

Type Description
Definition NK3 homeobox 2

研究结论

Date Results Publications
2018-03-10 10:03:00 these results suggest that Nkx3.2-mediated HIF regulation may allow cartilage-specific avascularity under hypoxic conditions during endochondral skeleton development. 28479297
2017-05-13 14:53:00 that cartilage-specific and Cre-dependent Nkx3.2 overexpression in mice results in significant postnatal dwarfism in endochondral skeletons 27253464
2012-12-29 10:27:00 Nkx3.2 promotes primary chondrogenesis by two mechanisms: Direct and Sox9-independent upregulation of Col2a1 transcription and upregulation of Sox9 mRNA expression under positive feedback system. 22511961
2012-11-17 10:24:00 the balance of Pax3, Nkx3.2 and Sox9 may act as a molecular switch during the chondrogenic differentiation of muscle progenitor cells, which may be important for fracture healing. 22768305
2012-01-28 12:10:00 These results demonstrated that Nkx3.2-dependent suppression of Runx2 was a crucial factor in hypoxia-dependent maintenance of chondrocyte identity. 22093831

名称对应

Type IDs
Synonymous Bapx1, NKX3.2, Nkx-3.2
Gene
UniProtKB-ID: NKX32_MOUSE
UniprotKB: P97503
UniParc: UPI00000230E6
EMBL: BC145874, BC145872, CH466524, U87957
Ensembl: ENSMUSG00000049691
KO: mmu:12020
Nucleutide sequences
EMBL-CDS: AAI45873.1, AAB47764.1, AAI45875.1, EDL37578.1
Ensembl_TRS: ENSMUST00000060820
Protein sequencees
Ensembl_PRO: ENSMUSP00000051990
RefSeq: NP_031550.2
Others
UniRef100: UniRef100_P97503
UniRef90: UniRef90_P97503
UniRef50: UniRef50_P97503
UniGene: Mm.2530
CCDS: CCDS19259.1

全选

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研究热度

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