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120071 LARGE2

120071

LARGE2

LARGE xylosyl- and glucuronyltransferase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition LARGE xylosyl- and glucuronyltransferase 2

研究结论

Date Results Publications
2016-03-26 10:27:00 Reduced levels of GYLTL1B and ISPD mRNA associated with increased patient mortality and are the likely cause of alphaDG hypoglycosylation in ccRCC. 26220087
2015-11-14 10:26:00 LARGE2 is negatively regulated by Snail and/or ZEB1, revealing a mechanistic basis for alphaDG hypoglycosylation during prostate cancer progression and metastasis. 25455932
2013-04-06 12:18:00 Loss of LARGE2 disrupts functional glycosylation of alpha-dystroglycan in prostate cancer 23223448
2010-04-07 21:40:00 Observational study of gene-disease association. (HuGE Navigator) 19724895
2010-04-07 21:40:00 Observational study of gene-disease association. (HuGE Navigator) 20198315

名称对应

Type IDs
Synonymous GYLTL1B, PP5656
Gene
UniProtKB-ID: LARG2_HUMAN, E9PIZ2_HUMAN, B3KP69_HUMAN
UniprotKB: Q8N3Y3, E9PIZ2, B3KP69
UniParc: UPI000004B63B, UPI000004B639, UPI00001A82A1
EMBL: AK096021, AK055829, CH471064, BC037291, AF258588, AK092526, AC068385
Ensembl: ENSG00000165905
KO: hsa:120071
Nucleutide sequences
EMBL-CDS: AAG23791.1, AAH37291.1, EAW68021.1, BAC03909.1, BAC04675.1, BAG51581.1
Gene_ORFName: PP5656
Ensembl_TRS: ENST00000531526, ENST00000401752, ENST00000325468, ENST00000529052
Protein sequencees
Ensembl_PRO: ENSP00000432869, ENSP00000385235, ENSP00000324570, ENSP00000431932
RefSeq: XP_011518192.1, XP_006718204.1, XP_011518193.1, NP_689525.3, XP_016872662.1, XP_011518191.1, NP_001287651.1, XP_011518190.1, NP_001287650.1, XP_011518188.1, XP_011518194.1, XP_005252844.1, XP_006718203.1, XP_011518195.1
Others
UniRef100: UniRef100_B3KP69, UniRef100_E9PIZ2, UniRef100_Q8N3Y3
UniRef90: UniRef90_Q8N3Y3, UniRef90_A0A4W2GAM2
UniRef50: UniRef50_Q8N3Y3
UniGene: Hs.86543
CCDS: CCDS31473.1

全选

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