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12006 Axin2

12006

Axin2

axin 2

protein-coding

Mus musculus

基因描述

Type Description
Definition axin 2

研究结论

Date Results Publications
2018-05-05 10:34:00 Study provides evidence that Axin2-expressing cells execute regeneration after skeletal injury. 27853243
2018-04-28 12:04:00 identify Rap1b acting downstream of Axin2 as a signaling interrogator for FGF and BMP. Genetic analysis reveals that Rap1b is essential for development of craniofacial and body skeletons. Axin2 regulates Rap1b through modulation of canonical BMP signaling. 28520221
2018-04-07 10:55:00 increased mesenchymal Wnt signaling inhibits the sequential formation of teeth, and suggest that Axin2/Runx2 antagonistic interactions modulate the level of mesenchymal Wnt/beta-catenin signaling, underlying the contrasting dental phenotypes caused by human AXIN2 and RUNX2 mutations 29437780
2017-12-30 12:41:00 we found that ESC-derived tissues at day 7 grown in Glasgow Minimum Expression Media (GMEM) containing knockout serum replacement (KSR) exhibited higher levels of expression of axin2, a Wnt target gene, than those grown in chemically defined medium 27151576
2017-12-16 12:08:00 Barx2 and Pax7 regulate the canonical Wnt target gene Axin2, which mediates critical feedback to terminate the transcriptional response to Wnt signals. 27144473

名称对应

Type IDs
Synonymous Axi1, Axil, Conductin
Gene
UniProtKB-ID: AXIN2_MOUSE, Q3UQK5_MOUSE
UniprotKB: O88566, Q3UQK5
UniParc: UPI00005AC121, UPI00001927F7
EMBL: AL662893, AF073788, AF205889, BC057338, CH466558, AK142333
Ensembl: ENSMUSG00000000142
KO: mmu:12006
Nucleutide sequences
EMBL-CDS: AAF22800.1, EDL34346.1, AAH57338.1, AAC26047.1, BAE25034.1
Ensembl_TRS: ENSMUST00000052915
Protein sequencees
Ensembl_PRO: ENSMUSP00000051331
RefSeq: XP_006532123.1, XP_006532122.1, XP_006532120.1, XP_006532121.1, NP_056547.3, XP_030101353.1
Others
UniRef100: UniRef100_O88566
UniRef90: UniRef90_O88566
UniRef50: UniRef50_Q9Y2T1
UniGene: Mm.71710
CCDS: CCDS25575.1

全选

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