| Type | Description |
|---|---|
| Definition | arginine vasopressin receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:04:00 | Upregulation of renal Na-K-2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway. | 32035616 |
| 2020-07-04 12:33:00 | Site-1 protease-derived (S1P-derived) soluble (pro)renin receptor (sPRR) participates in regulation of fluid homeostasis via targeting V2R. PF-429242 (S1P inhibitor) treatment or renal tubule-specific deletion of S1P impaired mice urine concentrating capability, which was rescued by sPRR-His. S1P-derived sPRR exerts a key role in determining renal V2R expression and, thus, urine concentrating capability. | 30944256 |
| 2018-06-16 11:54:00 | type-2 vasopressin receptor in polycystic kidney disease is targeted by green mamba peptide | 28630289 |
| 2017-08-19 12:38:00 | Data show that upon heteromer formation with secretin receptor (SCTR), R137H, a nephrogenic diabetes insipidus (NDI)-causing vasopressin receptor 2 (AVPR2) mutant that is defective in trafficking to cell surface, can functionally be rescued. | 27649563 |
| 2017-06-10 12:15:00 | Conditional inactivation of Elf5 in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 and Avpr2 genes. | 28215940 |
| Type | IDs |
|---|---|
| Synonymous | ADHR, DI1, DIR, ND1, V2R, VPV2R |
| Gene |
UniProtKB-ID:
V2R_MOUSE,
Q3SWS4_MOUSE,
Q3SWS1_MOUSE,
Q3KNZ4_MOUSE
UniprotKB:
O88721,
Q3SWS4,
Q3SWS1,
Q3KNZ4
UniParc:
UPI00005C3FDC,
UPI000002377D,
UPI00005B63CA
EMBL:
BC107005,
BC105662,
AJ310753,
FJ411230,
BC104731,
AJ006691,
BC104729,
BC104728,
AF133093,
AL672002,
FJ411231
Ensembl:
ENSMUSG00000031390
KO:
mmu:12000
|
| Nucleutide sequences |
EMBL-CDS:
CAA07187.1,
CAC34589.1,
AAI04729.1,
ACR39044.1,
AAI04730.1,
AAI05663.1,
ACR39045.1,
AAI04732.1,
AAI07006.1
Ensembl_TRS:
ENSMUST00000033765,
ENSMUST00000101470,
ENSMUST00000114395
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033765,
ENSMUSP00000099011,
ENSMUSP00000110037
RefSeq:
XP_006527819.1,
NP_001263227.1,
NP_062277.1,
XP_017173854.1,
NP_001263228.1
|
| Others |
UniRef100:
UniRef100_Q3KNZ4,
UniRef100_Q3SWS4,
UniRef100_O88721
UniRef90:
UniRef90_Q00788,
UniRef90_Q3KNZ4,
UniRef90_Q3SWS4
UniRef50:
UniRef50_Q3KNZ4,
UniRef50_Q00788,
UniRef50_Q3SWS4
UniGene:
Mm.383171
CCDS:
CCDS30216.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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