| Type | Description |
|---|---|
| Definition | serpin family A member 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:25:00 | Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis. | 31945348 |
| 2020-12-12 13:25:00 | Circulating Serpina3 levels predict the major adverse cardiac events in patients with myocardial infarction. | 31439424 |
| 2020-07-11 11:44:00 | regulates a discrete set of genes in melanoma cells, including SERPINA3, a novel duanyu18133 target gene, which is functionally involved in regulation of melanoma migration and invasion. Knockdown of duanyu18133 impaired cell migration and invasion, in part via regulation of its transcriptional target SERPINA3. | 31278347 |
| 2020-06-06 11:05:00 | Here, we show that these issues can be addressed concurrently, using the serpin human a1-antichymotrypsin (ACT) as a model. We have introduced up to 15 amino acid substitutions into ACT, converting it into a surrogate corticosteroid-binding globulin (CBG), thereby creating a new binding globulin (NewBG). | 31103428 |
| 2020-03-07 10:21:00 | the upregulated transcriptional activity of HNRNP-K mediated by SERPINA3 promotes HCC cell survival and proliferation and could be an indicator of poor prognosis for HCC patients. | 31121493 |
| Type | IDs |
|---|---|
| Synonymous | AACT, ACT, GIG24, GIG25 |
| Gene |
UniProtKB-ID:
AACT_HUMAN,
A0A024R6P0_HUMAN
UniprotKB:
P01011,
A0A024R6P0
UniParc:
UPI00001FDAD4,
UPI000052A441,
UPI000012509B
EMBL:
X68733,
BC034554,
X68737,
K01500,
X68734,
AB209060,
AK123091,
BC070265,
AY513275,
AY513276,
BC013189,
BC003559,
M18906,
X00947,
AF089747,
J05176,
CH471061,
X68735,
BC010530,
X68736
Ensembl:
ENSG00000196136
KO:
hsa:12
|
| Nucleutide sequences |
EMBL-CDS:
AAD08810.1,
BAG53869.1,
AAH34554.1,
AAT08029.1,
CAA25459.1,
AAA51559.1,
BAD92297.1,
CAA48671.1,
AAH13189.1,
AAA51543.1,
AAH10530.1,
AAA51560.1,
AAT08028.1,
AAH70265.1,
AAH03559.3,
EAW81590.1,
EAW81589.1
Gene_ORFName:
GIG25,
GIG24,
hCG_2039549
Ensembl_TRS:
ENST00000556968,
ENST00000467132,
ENST00000393080,
ENST00000393078
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376793,
ENSP00000450540,
ENSP00000376795,
ENSP00000452476
RefSeq:
NP_001371602.1,
NP_001076.2,
NP_001371601.1,
NP_001371603.1
|
| Others |
UniRef100:
UniRef100_P01011
UniRef90:
UniRef90_P01011
UniRef50:
UniRef50_P01011
UniGene:
Hs.534293,
Hs.710488
CCDS:
CCDS32150.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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