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11966 Atp6v1b2

11966

Atp6v1b2

ATPase, H+ transporting, lysosomal V1 subunit B2

protein-coding

Mus musculus

基因描述

Type Description
Definition ATPase, H+ transporting, lysosomal V1 subunit B2

研究结论

Date Results Publications
2019-12-21 10:28:00 atp6v1b2 knockdown zebrafish showed developmental defects in multiple organs and systems. However, Atp6v1b2 c.1516C>T knockin mice displayed obvious cognitive defects but normal hearing and cochlear morphology. Impaired hippocampal CA1 region and weaker interaction between the V1E and B2 subunits in Atp6v1b2(Arg506X//Arg506X) mice were observed 31257146
2016-05-07 12:12:00 ATP6V1B2 is a molecular target of SIRT1 in fat cells. 26177453
2011-01-01 11:24:00 Disruption of vacuolar H+-ATPase a3-B2 subunit interaction inhibited osteoclast bone resorption. 20837476
2010-01-21 00:00:00 Redistribution of Atp6v1b2 occurs from intracellular compartments into the apical membrane of epididymal clear cells from Atp6v1b1(-/-) mice. 17392376
2010-01-21 00:00:00 expressed in most, if not all, proton-secreting cells in the epithelium lining the nephron and the collecting ducts, and it is also present in proton-secreting clear cells of the epididymis 15013950

名称对应

Type IDs
Synonymous AI194269, AI790362, Atp6b2, HO57, R74844
Gene
UniProtKB-ID: VATB2_MOUSE
UniprotKB: P62814
UniParc: UPI0000001918
EMBL: AK151322, AK166669, BC085300, BC012497, AK151586, AK159701, AK152718, AK160854, AK152766, AK160080, AK159153, AK146499, AK159986, AK169270, BC046302, AK151200, AK168852, Y12634, AK159133, AK159586, U13838, AK169155
Ensembl: ENSMUSG00000006273
KO: mmu:11966
Nucleutide sequences
EMBL-CDS: AAC52411.1, AAH46302.1, BAE34860.1, AAH12497.1, BAE36047.1, BAE35612.1, BAE40674.1, BAE30303.1, BAE38930.1, BAE41031.1, BAE35536.1, BAE30197.1, AAH85300.1, BAE31479.1, BAE31441.1, BAE27215.1, BAE35206.1, BAE35300.1, BAE40934.1, BAE30526.1, BAE34845.1, CAA73182.1
Ensembl_TRS: ENSMUST00000006435
Protein sequencees
Ensembl_PRO: ENSMUSP00000006435
RefSeq: NP_031535.2
Others
UniRef100: UniRef100_P62814
UniRef90: UniRef90_P21281
UniRef50: UniRef50_P21281
UniGene: Mm.249096
CCDS: CCDS40358.1

全选

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