| Type | Description |
|---|---|
| Definition | CDC like kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 18:50:00 | LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation. | 31782550 |
| 2020-02-29 10:40:00 | found that CLK1 amplifies its presence in the nucleus by forming a stable complex with the Ser-Arg protein substrate | 31064840 |
| 2018-09-15 11:08:00 | We now show that the ability of SRPK1 to mobilize SRSF1 from speckles to the nucleoplasm is dependent on active CLK1. Diffusion from speckles is promoted by the formation of an SRPK1-CLK1 complex that facilitates dissociation of SRSF1 from CLK1 and enhances the phosphorylation of several serine-proline dipeptides in this SR protein | 29335301 |
| 2018-06-23 11:20:00 | Data suggest that CLK1 activity in both transformed and normal cells is carefully regulated via CLK1 alternative splicing through both exon 4 skipping and intron 4 retention. CLK1 autoregulates by favoring the expression of truncated isoforms, CLK1T1 and CLKT2 in environmental stress. | 29802995 |
| 2017-11-18 13:37:00 | These results thus reveal a large program of CLK1-regulated periodic alternative splicing intimately associated with cell cycle control. | 27015110 |
| Type | IDs |
|---|---|
| Synonymous | CLK, CLK/STY, STY |
| Gene |
UniProtKB-ID:
CLK1_HUMAN
UniprotKB:
P49759
UniParc:
UPI000006FE56,
UPI000002A6B0,
UPI00017A7024
EMBL:
L29219,
AC005037,
CH471063,
AK294295,
BC028149,
BC031549,
AK289365,
L29222
Ensembl:
ENSG00000013441
KO:
hsa:1195
|
| Nucleutide sequences |
EMBL-CDS:
EAW70217.1,
AAH28149.1,
BAF82054.1,
AAY14722.1,
AAB59459.1,
BAG57578.1,
AAA61480.1,
AAH31549.1
Ensembl_TRS:
ENST00000321356,
ENST00000432425,
ENST00000434813
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394734,
ENSP00000400487,
ENSP00000326830
RefSeq:
NP_004062.2,
NP_001155879.1
|
| Others |
UniRef100:
UniRef100_P49759
UniRef90:
UniRef90_P49759
UniRef50:
UniRef50_P49759
UniGene:
Hs.433732
CCDS:
CCDS2331.1,
CCDS54427.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员