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11944 Atp4a

11944

Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

protein-coding

Mus musculus

基因描述

Type Description
Definition ATPase, H+/K+ exchanging, gastric, alpha polypeptide

研究结论

Date Results Publications
2021-03-20 13:28:00 Dynamic characterization of intestinal metaplasia in the gastric corpus mucosa of Atp4a-deficient mice. 31904088
2019-03-02 10:56:00 Two genes, Atp4a and Pop4, fulfilled the criteria from our candidate gene approaches. The knockdown of both genes in MIN6 cells led to decreased glucose-stimulated insulin secretion, indicating a regulatory role of both genes in insulin secretion, thereby possibly contributing to the phenotype linked to Nbg7p 30341086
2018-10-06 10:19:00 the effect of GOAT on gastric acid secretion and expression of ghrelin in vitro, were investigated. 29966658
2017-08-12 10:19:00 ENaC activity in the cortical collecting duct of HKalpha1 H(+),K(+)-ATPase knockout mice is uncoupled from Na(+) intake. 28179253
2012-02-18 11:07:00 Point mutation in Atp4a (or Atp4a-/- knockout) results in achlorhydria and leads to iron-deficiency anemia; thus, functioning Atp4a is necessary for absorption of dietary iron leading to effective erythropoiesis. 21976678

名称对应

Type IDs
Gene
UniProtKB-ID: Q91WH7_MOUSE, E9QNX7_MOUSE
UniprotKB: Q91WH7, E9QNX7
UniParc: UPI00000E6A65, UPI000024D929
EMBL: AC167978, BC015262
Ensembl: ENSMUSG00000005553
KO: mmu:11944
Nucleutide sequences
EMBL-CDS: AAH15262.1
Ensembl_TRS: ENSMUST00000170371, ENSMUST00000005692
Protein sequencees
Ensembl_PRO: ENSMUSP00000131964, ENSMUSP00000005692
RefSeq: NP_061201.2, NP_001277556.1
Others
UniRef100: UniRef100_E9QNX7, UniRef100_Q91WH7
UniRef90: UniRef90_Q64436
UniRef50: UniRef50_P13607-7
UniGene: Mm.12821

全选

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研究热度

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